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CASK

calcium/calmodulin-dependent serine protein kinase (MAGUK family)

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Gene Name: calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Family/Subfamily: Protein Kinase , CASK
Synonyms: CASK, CAMGUK, Cask/lin-2, CMG, FGS4, LIN2, MICPCH, HCASK, Protein Kinase Cask, Protein lin-2 homolog, CAGH39, MRXSNA, TNRC8
Target Sequences: NM_003688 NP_003679.2 O14936

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).