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Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Gene Name: | caspase recruitment domain family, member 17 |
Family/Subfamily: | Protease , Provisional protease |
Synonyms: | CARD17, INCA, Inhibitory CARD, Caspase-1 inhibitor INCA |
Target Sequences: | AX350322 |
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