CARD16 / COP

caspase recruitment domain family, member 16

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

CARD16 / COP (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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CARD16 / COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121279

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.4 kDa

Price:

100 µg/$494

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CARD16 / COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108101

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.6 kDa

Price:

100 µg/$494

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Human CARD16 / COP Protein (Recombinant His, N-Terminal) - LS-G144127

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.4 kDa

Price:

50 µg/$419

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Human CARD16 / COP Protein (Recombinant GST) (Full Length) - LS-G36177

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

37.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CARD16 / COP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72573

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.6 kDa

Price:

20 µg/$1,107

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Human CARD16 / COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92909

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.6 kDa

Price:

20 µg/$150

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Human CARD16 / COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92910

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.4 kDa

Price:

20 µg/$150

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Human CARD16 / COP Protein (Recombinant GST, N-terminus) (aa1-97) - LS-G63538

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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