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CARD14

caspase recruitment domain family, member 14

CARD14 is a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.

Gene Name: caspase recruitment domain family, member 14
Synonyms: CARD14, BIMP2, Card-maguk protein 2, Carma 2, PrP, PSORS2, PSS1, CARMA2
Target Sequences: NM_024110 NP_077015.2 Q9BXL6

Publications (1)

1
Gain of function p.E138A alteration in Card14 leads to psoriasiform skin inflammation and implicates genetic modifiers in disease severity. John P Sundberg, C Herbert Pratt, Kathleen A Silva, Victoria E Kennedy, Wenning Qin, Timothy M Stearns, Jacqueline Frost, Beth A Sundberg, Anne M Bowcock. Experimental and molecular pathology. 2019 October;110:104286. [Full Text Article] [PubMed:31323190] [PMC:PMC7318844] Related Antibodies: LS-B11378.

☰ Filters
Antibodies (19)
Proteins (6)
Over-Expression Lysate (2)
Primary (19)
Recombinant (4)
CARD14 (25)
Human (19)
Mouse (6)
Rat (2)
IHC (6)
IHC-P (4)
WB (5)
ELISA (12)
ICC (1)
IF (4)
IP (1)
Peptide-ELISA (1)
rabbit (13)
mouse (6)
Product Group
IHCPlus (2)
IgG (11)
IgG2b,k (6)
monoclonal mc (6)
polyclonal pc (13)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
260-340 aa, Internal (1)
Internal (1)
aa291-340 (1)
aa905-1005 (1)
No (24)
Yes (1)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (1)
CARD14 Antibody - Anti-CARD14 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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CARD14 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
100 µl/$515
CARD14 Antibody - Immunohistochemical analysis of CARD14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CARD14 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
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CARD14 Rabbit anti-Human Polyclonal (260-340 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CARD14 Antibody - Anti-CARD14 / CARMA2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CARD14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
0.05 mg/$460
CARD14 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using CARD14 Polyclonal Antibody at dilution of 1:30.
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CARD14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CARD14 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using CARD14 Polyclonal Antibody at dilution of 1:30.
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CARD14 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CARD14 Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using CAR14 antibody.
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CARD14 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF
Unconjugated
100 µg/$357
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CARD14 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
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CARD14 Mouse anti-Human Monoclonal (aa905-1005) Antibody
Human
ELISA
Unconjugated
100 µg/$705
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CARD14 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
100 µl/$904
Select
CARD14 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$904
Select
CARD14 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
100 µl/$904
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CARD14 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA
PE Conjugated
100 µl/$904
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CARD14 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$904
CARD14 Antibody - Immunohistochemistry image of paraffin-embedded human breast cancer at a dilution of 1:100
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CARD14 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
CARD14 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
CARD14 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
CARD14 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
CARD14 Antibody - Western blot of CARD14 antibody at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: sp2/0 whole cell lysate. Lane 3: PC12 whole cell lysate.
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CARD14 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CARD14 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
113.1 kDa
100 µg/$710
CARD14 Protein - 12.5% SDS-PAGE of human CARD14 stained with Coomassie Blue
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Wheat Germ Extract
GST
74.9 kDa
10 µg/$479; 25 µg/$670
CARD14 Protein - Purified recombinant protein CARD14 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
113.1 kDa
20 µg/$1,107
CARD14 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
113.1 kDa
20 µg/$215
CARD14 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CARD14 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-25 of 25 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).