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Carboxypeptidase Z / CPZ

carboxypeptidase Z

The major form of CPZ mRNA in human salivary gland encodes a protein with an open reading frame of 641 amino acids. In addition, three variants were found that presumably arise due to alternative intron splicing. The 641 amino acid protein contains an 18 residue signal peptide-like sequence, a 120 residue region that shows 23-29% amino acid identity with a Cys-rich domain found in frizzled proteins and in type XVIII collagen, and then a 390 residue carboxypeptidase domain with 49% amino acid identity to carboxypeptidases E and N. The CPZ activity is more active at neutral pH than at pH 5.5 and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. CPZ is a metallocarboxypeptidase that is active toward substrates with C-terminal basic amino acids.

Gene Name: carboxypeptidase Z
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPZ, Carboxypeptidase Z, Metallocarboxypeptidase Z
Target Sequences: NM_003652 NP_003643.2 Q66K79

☰ Filters
Antibodies (16)
Proteins (5)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (16)
Recombinant (1)
Sandwich (1)
Carboxypeptidase Z / CPZ (22)
Human (13)
Rat (6)
IHC (1)
IHC-P (1)
WB (12)
ELISA (6)
IF (1)
Peptide-ELISA (1)
rabbit (16)
IgG (7)
polyclonal pc (16)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (6)
aa425-652 (8)
330-410 aa, Internal (1)
aa143-172 (1)
No (22)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Carboxypeptidase Z / CPZ Antibody - Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa143-172) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Carboxypeptidase Z / CPZ Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (330-410 aa, Internal) Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
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Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
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Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
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Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Carboxypeptidase Z / CPZ Antibody - Western blot of Carboxypeptidase Z / CPZ antibody.
Select
Carboxypeptidase Z / CPZ Rabbit anti-Human Polyclonal (aa425-652) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
Carboxypeptidase Z / CPZ Antibody - Western Blot Positive WB detected in: HEK293 whole cell lysate, A549 whole cell lysate, U87 whole cell lysate All lanes: CPZ antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 74, 73, 59 kDa Observed band size: 74, 59 kDa
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Carboxypeptidase Z / CPZ Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
Carboxypeptidase Z / CPZ Rabbit anti-Rat Polyclonal (HRP) Antibody
Rat
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
Carboxypeptidase Z / CPZ Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
Carboxypeptidase Z / CPZ Rabbit anti-Rat Polyclonal (FITC) Antibody
Rat
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Carboxypeptidase Z / CPZ Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
73.63 kDa
20 µg/$150
Carboxypeptidase Z / CPZ Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
72.5 kDa
20 µg/$215
Carboxypeptidase Z / CPZ Protein - Recombinant Carboxypeptidase Z By SDS-PAGE
Select
E. coli
His-T7
29.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Carboxypeptidase Z / CPZ Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
72.5 kDa
100 µg/$710
Carboxypeptidase Z / CPZ ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
Carboxypeptidase Z / CPZ Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
73.63 kDa
100 µg/$494
Viewing 1-22 of 22 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).