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CAPN2 / Calpain 2 / M-Calpain
calpain 2, (m/II) large subunit
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | calpain 2, (m/II) large subunit |
| Family/Subfamily: | Protease , Cysteine C2 |
| Synonyms: | CAPN2, Calpain 2, large subunit, Calpain ii, Calpain, large polypeptide L2, Calpain-2 catalytic subunit, Calpain 2, Calpain large polypeptide L2, Calpain-2 large subunit, CANP 2, Calpain M-type, CANP2, CANPL2, CANPml, M-type calpain, M-calpain, MCANP, Millimolar-calpain |
| Target Sequences: | NM_001748 NP_001739.2 P17655 |
Publications (2)
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