CAPN10 / Calpain 10

calpain 10

Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CAPN10 / Calpain 10 (4)

Publications

No (4)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CAPN10 / Calpain 10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84768

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.8 kDa

Price:

20 µg/$150

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Mouse CAPN10 / Calpain 10 Protein (Recombinant His) (aa22-374) - LS-G25183

Source:

E. coli

Tag:

His

Molecular Weight:

44.1 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human CAPN10 / Calpain 10 Protein (Recombinant GST) (Full Length) - LS-G32520

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

101.3 kDa

Price:

2 µg/$439

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CAPN10 / Calpain 10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110200

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.8 kDa

Price:

100 µg/$494

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