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CANX / Calnexin
calnexin
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
| Gene Name: | calnexin |
| Synonyms: | CANX, CNX, Calnexin, IP90, p90 |
| Target Sequences: | NM_001746 NP_001737.1 P27824 |
Publications (4)
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