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CAND2 / TIP120B

cullin-associated and neddylation-dissociated 2 (putative)

Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.

Gene Name: cullin-associated and neddylation-dissociated 2 (putative)
Synonyms: CAND2, KIAA0667, p120 CAND2, TBP interacting protein, TIP120B, TBP-interacting protein 120B, Tp120b
Target Sequences: NP_036430.1 O75155

Publications (3)

1
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Liu J, Furukawa M, Matsumoto T, Xiong Y. Molecular cell. 2002 10:1511-8. [PubMed:12504025] Related Antibodies: LS-B348.
2
AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis. Cheng Y, Dai X, Zhao Y. Plant physiology. 2004 135:1020-6. [PubMed:15181201] [PMC:PMC514136] Related Antibodies: LS-B348.
3
Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation. Feng S, Shen Y, Sullivan JA, Rubio V, Xiong Y, Sun TP, Deng XW. The Plant cell. 2004 16:1870-82. [PubMed:15208391] [PMC:PMC514167] Related Antibodies: LS-B348.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
CAND2 / TIP120B (3)
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Myc-DDK (Flag) (3)
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293T Cells (1)
HEK 293 Cells (2)
CAND2 / TIP120B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
135.1 kDa
100 µg/$710
CAND2 / TIP120B Protein - Purified recombinant protein CAND2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
135.1 kDa
20 µg/$1,107
CAND2 / TIP120B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
135.1 kDa
20 µg/$215
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).