CAMKK2

calcium/calmodulin-dependent protein kinase kinase 2, beta

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca2+ signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

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Products

Proteins (14)

Type

Over-Expression Lysate (10)

Recombinant (4)

Target

CAMKK2 (14)

Publications

No (14)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (12)

Species

Human (9)

Source

293T Cells (5)

HEK 293 Cells (7)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CAMKK2 Protein (Recombinant GST, N-terminus) (aa1-130) - LS-G61593

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CAMKK2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68825

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.4 kDa

Price:

20 µg/$1,107

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Human CAMKK2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68824

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.4 kDa

Price:

20 µg/$1,107

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Human CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83184

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.4 kDa

Price:

20 µg/$215

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Human CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83193

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.7 kDa

Price:

20 µg/$215

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Human CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83185

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.6 kDa

Price:

20 µg/$215

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Human CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83186

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

20 µg/$215

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Human CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83187

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.8 kDa

Price:

20 µg/$215

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Human CAMKK2 Protein (Recombinant GST) (Full Length) - LS-G32278

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

86 kDa

Price:

10 µg/$479; 25 µg/$670

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CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105746

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.4 kDa

Price:

100 µg/$710

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CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105748

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.6 kDa

Price:

100 µg/$710

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CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105474

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.7 kDa

Price:

100 µg/$710

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CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105475

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

100 µg/$710

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CAMKK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105476

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.8 kDa

Price:

100 µg/$710

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