CAMK2B / CaMKII Beta

calcium/calmodulin-dependent protein kinase II beta

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.

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Products

Proteins (21)

Type

Over-Expression Lysate (16)

Recombinant (5)

Target

CAMK2B / CaMKII Beta (21)

Publications

No (21)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His-S (1)

Myc-DDK (Flag) (17)

Species

Human (13)

Source

293T Cells (8)

E. coli (2)

HEK 293 Cells (9)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105555

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.8 kDa

Price:

100 µg/$710

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105553

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.8 kDa

Price:

100 µg/$710

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105557

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.8 kDa

Price:

100 µg/$710

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105556

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.7 kDa

Price:

100 µg/$710

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105559

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

100 µg/$710

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105551

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.2 kDa

Price:

100 µg/$710

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105554

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.2 kDa

Price:

100 µg/$494

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CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118714

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.4 kDa

Price:

100 µg/$710

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Human CAMK2B / CaMKII Beta Protein (Recombinant His-S) (aa1-301) - LS-G25259

Source:

E. coli

Tag:

His-S

Molecular Weight:

41.7 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human CAMK2B / CaMKII Beta Protein (Recombinant GST) (Full Length) - LS-G27729

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.07 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CAMK2B / CaMKII Beta Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68459

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.2 kDa

Price:

20 µg/$1,107

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Human CAMK2B / CaMKII Beta Protein (Recombinant GST, N-terminus) (aa405-502) - LS-G57970

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82225

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.8 kDa

Price:

20 µg/$215

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Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82224

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.2 kDa

Price:

20 µg/$215

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Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82226

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.2 kDa

Price:

20 µg/$150

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Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82227

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.8 kDa

Price:

20 µg/$215

Select

Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82229

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

20 µg/$215

Select

Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82230

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.8 kDa

Price:

20 µg/$215

Select

Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82228

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.7 kDa

Price:

20 µg/$215

Select

Human CAMK2B / CaMKII Beta Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82231

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.4 kDa

Price:

20 µg/$215

Select

Human CAMK2B / CaMKII Beta Protein (Recombinant 6His, C-terminus) (Met1-Gln503) - LS-G39669

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.4kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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