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CALU / Calumenin
Calumenin
Calumenin (CALU) is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting. Calumenin is a member of the EF-hand superfamily in the ER and Golgi apparatus named CERC. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55, and calumenin. The CALU gene encodes a deduced 315-amino acid protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal. The human and mouse CALU proteins are 98% identical. CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.
| Gene Name: | Calumenin |
| Synonyms: | CALU, Crocalbin, Multiple EF-hand protein, Calumenin, Crocalbin-like protein, IEF SSP 9302 |
| Target Sequences: | NM_001219 NP_001210.1 O43852 |
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