CALM2 / Calmodulin 2

calmodulin 2 (phosphorylase kinase, delta)

CALM2 / Calmodulin 2 is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

CALM2 / Calmodulin 2 (7)

Publications

No (7)

Tag

GST (2)

His,N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (4)

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Human CALM2 / Calmodulin 2 Protein (Recombinant His,N-terminus) (Met1-Lys149) - LS-G137969

Source:

E. coli

Tag:

His,N-terminus

Molecular Weight:

18.7 kDa

Price:

100 µg/$502

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Human CALM2 / Calmodulin 2 Protein (Recombinant GST) (Full Length) - LS-G27720

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.13 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CALM2 / Calmodulin 2 Protein (Recombinant GST) (Full Length) - LS-G27721

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

43.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CALM2 / Calmodulin 2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67823

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

16.7 kDa

Price:

20 µg/$1,107

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Human CALM2 / Calmodulin 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80787

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

16.7 kDa

Price:

20 µg/$150

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CALM2 / Calmodulin 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99543

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

16.7 kDa

Price:

100 µg/$494

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Human CALM2 / Calmodulin 2 Protein (Recombinant) - LS-G3358

Source:

E. coli

Tag:

None

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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