CALHM1

calcium homeostasis modulator 1

Pore-forming subunit of a voltage-gated ion channel required for sensory perception of sweet, bitter and umami tastes. Specifically present in type II taste bud cells, where it plays a central role in sweet, bitter and umami taste perception by inducing ATP release from the cell, ATP acting as a neurotransmitter to activate afferent neural gustatory pathways. Acts both as a voltage-gated and calcium-activated ion channel: mediates neuronal excitability in response to changes in extracellular Ca2+ concentration. Has poor ion selectivity and forms a wide pore (around 14 Angstroms) that mediates permeation of Ca2+, Na+ and K+, as well as permeation of monovalent anions. Acts as an activator of the ERK1 and ERK2 cascade. Triggers endoplasmic reticulum stress by reducing the calcium content of the endoplasmic reticulum. May indirectly control amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca2+ dependent manner.

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Products

Antibodies (17)

Type

Primary (17)

Target

CALHM1 (17)

Reactivity

Human (15)

Mouse (9)

Rat (9)

Hamster (3)

Application

IHC (10)

IHC-P (3)

WB (14)

ELISA (8)

IF (1)

Host

rabbit (17)

Isotype

IgG (11)

Clonality

polyclonal pc (17)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (14)

Epitope

C-Terminus (3)

aa202-346 (2)

aa250-300 (1)

aa295-344 (1)

Publications

No (17)

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CALHM1 Antibody (aa295-344) LS-C145210

Antibody:

CALHM1 Rabbit anti-Mouse Polyclonal (aa295-344) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CALHM1 Antibody (C-Terminus, HRP) LS-C446500

Antibody:

CALHM1 Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Mouse, Rat, Hamster, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CALHM1 Antibody (C-Terminus, Biotin) LS-C446498

Antibody:

CALHM1 Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Rat, Hamster, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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CALHM1 Antibody (C-Terminus, FITC) LS-C446499

Antibody:

CALHM1 Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Rat, Hamster, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CALHM1 Antibody (aa250-300) LS-C483032

Antibody:

CALHM1 Rabbit anti-Mouse Polyclonal (aa250-300) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$393

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CALHM1 Antibody LS-C108656

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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CALHM1 Antibody LS-C140642

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$466

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CALHM1 Antibody LS-C659813

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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CALHM1 Antibody LS-C750917

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$466

Select

CALHM1 Antibody (aa202-346) LS-C378013

Antibody:

CALHM1 Rabbit anti-Human Polyclonal (aa202-346) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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CALHM1 Antibody LS-C413633

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$321

Select

CALHM1 Antibody LS-C765040

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CALHM1 Antibody LS-C830445

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CALHM1 Antibody LS-C831936

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CALHM1 Antibody LS-C409407

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

CALHM1 Antibody (aa202-346) LS-C378011

Antibody:

CALHM1 Rabbit anti-Human Polyclonal (aa202-346) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

CALHM1 Antibody LS-C826561

Antibody:

CALHM1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

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