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CALCRL / CGRP Receptor

calcitonin receptor-like

Calcitonin receptor-like receptor (CRLR) is an Adrenomedullin Receptor that requires two additional proteins to function: a chaperone protein RAMP (receptor activity modifying protein) and the component protein RCP. The function of CRLR depends on its interaction with RAMP. When coexpressed with RAMP1, CRLR acts as a receptor for calcitonin gene-related peptide (CGRP). In contrast, when CRLR is coexpressed with either RAMP2 or RAMP3, it acts as a receptor for adrenomedullin. Activation of the receptor leads to an increase in intracellular cyclic AMP. CRLR mediates the vasorelaxation of arteries, suggesting a potential role for the receptor in reaction to injury, particularly in the treatment of pulmonary hypertension.

Gene Name: calcitonin receptor-like
Family/Subfamily: GPCR , Adrenomedullin
Synonyms: CALCRL, CGRP type 1 receptor, Cgrp1 receptor, CRLR, Calcitonin receptor-like, CGRP receptor, CGRPR
Target Sequences: NM_005795 NP_005786.1 Q16602

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Products
ELISA Kits (6)
Competitive EIA (1)
Custom (2)
Sandwich (3)
CALCRL / CGRP Receptor (6)
Human (2)
Mouse (1)
Rat (1)
Bovine (1)
Pig (1)
96-Well Strip Plate (6)
No (6)
Plasma (4)
Serum (4)
Tissue Homogenates (1)
CALCRL / CGRP Receptor ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CALCRL / CGRP Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
1 Plate/$783
CALCRL / CGRP Receptor ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CALCRL / CGRP Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Bovine
1 Plate/$783
CALCRL / CGRP Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CALCRL / CGRP Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).