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CALB1 / Calbindin
calbindin 1, 28kDa
CALB1 / Calbindin is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.
| Gene Name: | calbindin 1, 28kDa |
| Synonyms: | CALB1, Calbindin D28, Calbindin, Calbindin 1, 28kDa, CAB27, CALB, RTVL-H protein, Calbindin 1, (28kD), D-28K |
| Target Sequences: | NM_004929 NP_004920.1 P05937 |
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