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CACNG3

calcium channel, voltage-dependent, gamma subunit 3

CACNG3 (Voltage-dependent calcium channel gamma-3 subunit, Cav ?3) regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Gene Name:	calcium channel, voltage-dependent, gamma subunit 3
Family/Subfamily:	Ion Channel , Calcium channel - gamma subunit
Synonyms:	CACNG3, Gamma 3, TARP gamma-3
Target Sequences:	NM_006539 NP_006530.1 O60359

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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