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CACNA2D4

calcium channel, voltage-dependent, alpha 2/delta subunit 4

CACNA2D4 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Family/Subfamily: Ion channel , Calcium channel - alpha subunit 2 / delta
Synonyms: CACNA2D4, RCD4
Target Sequences: AF516695 AAN06672.1 Q7Z3S7

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).