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CACNA1F / Cav1.4

calcium channel, voltage-dependent, L type, alpha 1F subunit

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).

Gene Name:	calcium channel, voltage-dependent, L type, alpha 1F subunit
Family/Subfamily:	Ion Channel , Calcium channel - alpha subunit Cav1
Synonyms:	CACNA1F, AIED, Alpha 1f, Cav1.4, CORDX, CSNXB2, Ca(v)1.4, CACNAF1, Cav1.4alpha1, CSNBX2, COD3, COD4, CORDX3, CSNB2, CSNB2A, JMC8, JM8, OA2
Target Sequences:	NM_005183 NP_005174.2 O60840

Publications (1)

LKB1 and AMPK regulate synaptic remodeling in old age. Samuel MA, Voinescu PE, Lilley BN, de Cabo R, Foretz M, Viollet B, Pawlyk B, Sandberg MA, Vavvas DG, Sanes JR. Nature neuroscience. 2014 17:1190-7. (IHC; Human) [Full Text Article] [PubMed:25086610] [PMC:PMC5369022] Related Antibodies: LS-C94032.

Mouse CACNA1F / Cav1.4 (Sandwich ELISA) ELISA Kit - LS-F8775

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$854

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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