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CACNA1F / Cav1.4

calcium channel, voltage-dependent, L type, alpha 1F subunit

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).

Gene Name: calcium channel, voltage-dependent, L type, alpha 1F subunit
Family/Subfamily: Ion Channel , Calcium channel - alpha subunit Cav1
Synonyms: CACNA1F, AIED, Alpha 1f, Cav1.4, CORDX, CSNXB2, Ca(v)1.4, CACNAF1, Cav1.4alpha1, CSNBX2, COD3, COD4, CORDX3, CSNB2, CSNB2A, JMC8, JM8, OA2
Target Sequences: NM_005183 NP_005174.2 O60840

Publications (1)

1
LKB1 and AMPK regulate synaptic remodeling in old age. Samuel MA, Voinescu PE, Lilley BN, de Cabo R, Foretz M, Viollet B, Pawlyk B, Sandberg MA, Vavvas DG, Sanes JR. Nature neuroscience. 2014 17:1190-7. (IHC; Human) [Full Text Article] [PubMed:25086610] [PMC:PMC5369022] Related Antibodies: LS-C94032.

☰ Filters
Antibodies (4)
Proteins (3)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (4)
Recombinant (1)
Sandwich (1)
CACNA1F / Cav1.4 (8)
Human (4)
Mouse (2)
IHC (1)
WB (4)
ELISA (2)
Peptide-ELISA (1)
rabbit (3)
mouse (1)
IgG (1)
IgG3,k (1)
monoclonal mc (1)
polyclonal pc (3)
3B2 (1)
96-Well Strip Plate (1)
Unconjugated (4)
aa1700-1750 (1)
aa743-776 (1)
No (7)
Yes (1)
Tissue Homogenates (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Select
CACNA1F / Cav1.4 Rabbit anti-Human Polyclonal (aa1700-1750) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
Select
CACNA1F / Cav1.4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
CACNA1F / Cav1.4 Antibody - Detection limit for recombinant GST tagged CACNA1F is approximately 0.3 ng/ml as a capture antibody.
Select
CACNA1F / Cav1.4 Mouse anti-Human Monoclonal (3B2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$554
CACNA1F / Cav1.4 Antibody - All lanes: Anti-CACNA1F Antibody (Center) at 1:2000 dilution. Lane 1: A-673 whole cell lysate. Lane 2: Y79 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 221 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
CACNA1F / Cav1.4 Rabbit anti-Human Polyclonal (aa743-776) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
CACNA1F / Cav1.4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CACNA1F / Cav1.4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
220.5 kDa
20 µg/$215
CACNA1F / Cav1.4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
220.5 kDa
100 µg/$710
CACNA1F / Cav1.4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$854
Viewing 1-8 of 8 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).