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CA3 / Carbonic Anhydrase III
carbonic anhydrase III, muscle specific
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.
| Gene Name: | carbonic anhydrase III, muscle specific |
| Synonyms: | CA3, Carbonate dehydratase III, Carbonic anhydrase 3, Carbonic anhydrase III, CA-III, CAIII, Car3 |
| Target Sequences: | NM_005181 NP_005172.1 P07451 |
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