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CA2 / Carbonic Anhydrase II
carbonic anhydrase II
Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
| Gene Name: | carbonic anhydrase II |
| Synonyms: | CA2, CA-II, CAII, CAC, Car2, Carbonate dehydratase II, Carbonic anhydrase C, Carbonic anhydrase II, Carbonic dehydratase, Carbonic anhydrase 2, Carbonic anhydrase B |
| Target Sequences: | NM_000067 NP_000058.1 P00918 |
Publications (6)
1
Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger. Li X, Alvarez B, Casey JR, Reithmeier RA, Fliegel L. The Journal of biological chemistry. 2002 277:36085-91.
[PubMed:12138085]
2
Inhibition of cell growth and nuclear factor-kappaB activity in pancreatic cancer cell lines by a tylophorine analogue, DCB-3503. Shiah HS, Gao W, Baker DC, Cheng YC. Molecular cancer therapeutics. 2006 5:2484-93.
[PubMed:17041092]
3
Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cells. Li Y, Tu C, Wang H, Silverman DN, Frost SC. The Journal of biological chemistry. 2011 286:15789-96.
[PubMed:21454639]
[PMC:PMC3091188]
☰ Filters
Products
Proteins
(23)
Type
Native
(7)
Over-Expression Lysate
(2)
Recombinant
(14)
Target
CA2 / Carbonic Anhydrase II
(23)
Publications
No
(23)
Tag
GST
(1)
GST, N-terminus
(1)
His
(7)
His, N-Terminal
(1)
His-SUMO
(1)
Myc-DDK (Flag)
(3)
Species
Chicken
(1)
Dog
(1)
Human
(10)
Mouse
(2)
Rabbit
(1)
Rat
(3)
Rhesus monkey
(2)
Sheep
(2)
Source
293T Cells
(1)
Dog
(1)
E. coli
(10)
HEK 293 Cells
(2)
Human
(1)
Mouse
(1)
Rabbit
(1)
Rat
(2)
Rhesus monkey
(1)
Sheep
(1)
Wheat Germ Extract
(2)
Purification
Purified
(8)
Biologically Active
Biologically active
(1)
Dog
None
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
E. coli
None
Biologically active
100 µg/$411; 500 µg/$985; 20 µg/$276
Human
None
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
HEK 293 Cells
Myc-DDK (Flag)
29.1 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
29.1 kDa
20 µg/$150
E. coli
His
30 kDa
100 µg/$502
Mouse
None
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
Rat
None
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Rabbit
None
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
His
30.5 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
E. coli
His
30.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His
30.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
None
10 µg/$299; 50 µg/$442; 100 µg/$662
Sheep
None
30.0 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
Rhesus monkey
None
30.5 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
His-SUMO
45 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His
30.6 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
E. coli
His
30.8 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
Wheat Germ Extract
GST
55.6 kDa
10 µg/$479; 25 µg/$670
Rat
His, N-Terminal
29kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
Wheat Germ Extract
GST, N-terminus
33.33 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
29.1 kDa
100 µg/$494
E. coli
His
30.4 kDa
100 µg/$661; 1 mg/$3,499
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