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C9orf72 / ALSFTD

Chromosome 9 open reading frame 72

C9orf72 plays an important role in the regulation of endosomal trafficking, and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Studies suggest that hexanucleotide expansions could result in the selective stabilization of repeat-containing pre-mRNA, and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093). Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: Chromosome 9 open reading frame 72
Synonyms: C9orf72
Target Sequences: NM_145005 NP_659442.2

☰ Filters
Antibodies (16)
Proteins (3)
Over-Expression Lysate (2)
Primary (16)
Recombinant (1)
C9orf72 / ALSFTD (19)
Human (16)
Mouse (2)
Rat (2)
IHC (4)
WB (12)
ELISA (14)
ICC (1)
IF (2)
IP (2)
Peptide-ELISA (1)
rabbit (15)
mouse (1)
IgG (14)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (15)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (8)
aa396-424 (7)
No (19)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Select
C9orf72 / ALSFTD Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$351
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
C9orf72 / ALSFTD Antibody - Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 µg/ml.
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, WB
Unconjugated
0.1 mg/$460
C9orf72 / ALSFTD Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
C9orf72 / ALSFTD Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using C9orf72 Antibody at dilution of 1:100
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
C9orf72 / ALSFTD Antibody - C9orf72 Antibody western blot of WiDr cell lysate (35 ug/lane). This demonstrates that the C9orf72 antibody detected C9orf72 protein (arrow).
Select
C9orf72 / ALSFTD Rabbit anti-Human Polyclonal (aa396-424) Antibody
Human
WB
Unconjugated
400 µl/$393
C9orf72 / ALSFTD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24.6 kDa
20 µg/$150
C9orf72 / ALSFTD Protein - 12.5% SDS-PAGE of human C9orf72 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
80.7 kDa
10 µg/$479; 25 µg/$670
C9orf72 / ALSFTD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.6 kDa
100 µg/$494
Viewing 1-19 of 19 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).