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C8orf4

Chromosome 8 Open Reading Frame 4

C8orf4 is a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

Gene Name: Chromosome 8 Open Reading Frame 4
Synonyms: C8orf4, Thyroid cancer protein 1, HTC-1, Human thyroid cancer 1, TC-1, TC1
Target Sequences: NM_020130 NP_064515.1 Q9NR00

☰ Filters
Antibodies (9)
Proteins (4)
Over-Expression Lysate (2)
Primary (9)
Recombinant (2)
C8orf4 (13)
Human (9)
Mouse (4)
Rat (5)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
Monkey (3)
Orangutan (3)
IHC (5)
IHC-P (1)
WB (5)
ELISA (3)
rabbit (9)
IgG (5)
polyclonal pc (9)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (6)
aa29-78 (4)
No (13)
GST, N-terminus (2)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
C8orf4 Antibody - Immunohistochemistry of paraffin-embedded rat lung tissue.
Select
C8orf4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
C8orf4 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer tissue at dilution 1:100
Select
C8orf4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
C8orf4 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer tissue  using C8orf4 Polyclonal Antibody at dilution of 1:55(×200)
Select
C8orf4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
C8orf4 Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using C8orf4 Polyclonal Antibody at dilution of 1:70(×200)
Select
C8orf4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
C8orf4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
C8orf4 Antibody - C8orf4 antibody Western Blot of 293T.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
C8orf4 Rabbit anti-Human Polyclonal (aa29-78) Antibody
Human
WB
Unconjugated
100 µl/$424
C8orf4 Antibody - C8orf4 antibody Western Blot of 293T.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
C8orf4 Rabbit anti-Human Polyclonal (aa29-78) (HRP) Antibody
Rat, Guinea pig, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
C8orf4 Antibody - C8orf4 antibody Western Blot of 293T.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
C8orf4 Rabbit anti-Human Polyclonal (aa29-78) (Biotin) Antibody
Rat, Guinea pig, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
C8orf4 Antibody - C8orf4 antibody Western Blot of 293T.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
C8orf4 Rabbit anti-Human Polyclonal (aa29-78) (FITC) Antibody
Rat, Guinea pig, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
C8orf4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
C8orf4 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
C8orf4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
12.2 kDa
20 µg/$150
C8orf4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
12.2 kDa
100 µg/$494
Viewing 1-13 of 13 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).