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C6orf150 / MB21D1

Mab-21 domain containing 1

Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to and activates TMEM173/STING, thereby triggering type-I interferon production.

Gene Name: Mab-21 domain containing 1
Synonyms: MB21D1, C6orf150, Mab-21 domain containing 1, Protein MB21D1
Target Sequences: Q8N884 Q8N884

☰ Filters
Antibodies (28)
Proteins (7)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (28)
Recombinant (5)
Sandwich (1)
C6orf150 / MB21D1 (36)
Human (29)
Mouse (8)
IHC (1)
IHC-P (1)
WB (28)
Flo (7)
ELISA (8)
Peptide-ELISA (1)
rabbit (27)
mouse (1)
IgG (8)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (27)
1697CT136.65.30 (1)
96-Well Microplate (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (9)
aa211-395 (8)
aa225-407 (8)
aa266-295 (7)
No (36)
Cell Lysates (1)
Tissue Homogenates (1)
6His-SUMO, N-terminus (1)
GST, N-terminus (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (5)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
C6orf150 / MB21D1 Antibody - Western blot of lysates from HT-29, THP-1 cell line, human cerebellum tissue lysate (from left to right), using CF150 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
C6orf150 / MB21D1 Antibody - All lanes: Anti-MB21D1 Antibody at 1:4000 dilution Lane 1: THP-1 whole cell lysate Lane 2: MDA-MB-231 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 59kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
C6orf150 / MB21D1 Mouse anti-Human Monoclonal (1697CT136.65.30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$355; 200 µl/$417; 500 µl/$635; 1 ml/$792; 2 ml/$1,030; 5 ml/$1,803
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$366; 200 µl/$432; 500 µl/$683; 1 ml/$842; 2 ml/$1,088; 5 ml/$1,941
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (PE) Antibody
Mouse, Human
WB
PE Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (APC, Cy7) Antibody
Mouse, Human
WB
APC, Cy7 Conjugated
100 µl/$543; 200 µl/$732; 500 µl/$1,268; 1 ml/$1,585; 2 ml/$2,219; 5 ml/$4,159
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (APC) Antibody
Mouse, Human
WB
APC Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Mouse Polyclonal (aa211-395) (Cy3) Antibody
Mouse, Human
WB
Cy3 Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa266-295) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
C6orf150 / MB21D1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
C6orf150 / MB21D1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
58.6 kDa
20 µg/$215
C6orf150 / MB21D1 Protein - Recombinant  Mab21 Domain Containing Protein 1 By SDS-PAGE
Select
E. coli
His-T7
24.9kd
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
HEK 293 Cells
Myc-DDK (Flag)
58.6 kDa
20 µg/$1,107
C6orf150 / MB21D1 Antibody
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
C6orf150 / MB21D1 Antibody - Western blot analysis of HT-29 and Lovo cell lysates  using CGAS Polyclonal Antibody at dilution of 1:400
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
C6orf150 / MB21D1 Antibody
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
C6orf150 / MB21D1 Antibody - Western blot of C6orf150 / MB21D1 antibody.
Select
C6orf150 / MB21D1 Rabbit anti-Human Polyclonal (aa225-407) Antibody
Human
WB
Unconjugated
100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345
Viewing 1-25 of 36 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).