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C5AR1 / CD88 / C5a Receptor

complement component 5a receptor 1

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene Name: complement component 5a receptor 1
Family/Subfamily: GPCR , Anaphylatoxin
Synonyms: C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen
Target Sequences: NM_001736 NP_001727.1 P21730

Publications (2)

1
A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA. Mehta G, Scheinman RI, Holers VM, Banda NK. Journal of immunology (Baltimore, Md. : 1950). 2015 194:5446-54. (Flo; Mouse) [Full Text Article] [PubMed:25917104] [PMC:PMC4433857] Related Antibodies: LS-C209596.
2
Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. Kavita Bisht, Giacomo Canesin, Tasneem Cheytan, Mailin Li, Zsuzsanna Nemeth, Eva Csizmadia, Trent M Woodruff, David E Stec, Andrew C Bulmer, Leo E Otterbein, Barbara Wegiel. Journal of immunology (Baltimore, Md. : 1950). 2019 May;202:2982-2990. [Full Text Article] [PubMed:30952817] [PMC:PMC6504595] Related Antibodies: LS-B5229.

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
C5AR1 / CD88 / C5a Receptor (6)
No (6)
GST (2)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (2)
C5AR1 / CD88 / C5a Receptor Protein - Purified recombinant protein C5AR1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
39.1 kDa
20 µg/$1,107
C5AR1 / CD88 / C5a Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
C5AR1 / CD88 / C5a Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
39.1 kDa
20 µg/$150
C5AR1 / CD88 / C5a Receptor Protein - 12.5% SDS-PAGE of human C5R1 stained with Coomassie Blue
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Wheat Germ Extract
GST
65.7 kDa
2 µg/$439
C5AR1 / CD88 / C5a Receptor Protein - 12.5% SDS-PAGE of human C5R1 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.24 kDa
2 µg/$439
C5AR1 / CD88 / C5a Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.1 kDa
100 µg/$494
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).