C1QTNF2 / CTRP2

C1q and tumor necrosis factor related protein 2

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-a-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

C1QTNF2 / CTRP2 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human C1QTNF2 / CTRP2 Protein (Recombinant GST) (Full Length) - LS-G36197

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.44 kDa

Price:

2 µg/$439

Select

Human C1QTNF2 / CTRP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92072

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

20 µg/$150

Select

C1QTNF2 / CTRP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102013

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

100 µg/$494

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.