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C1D

C1D nuclear receptor corepressor

Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.

Gene Name:	C1D nuclear receptor corepressor
Synonyms:	C1D, C1D DNA-binding protein, HC1D, Nuclear DNA-binding protein, SUNCOR, SUN-CoR
Target Sequences:	NM_006333 NP_006324.1 Q13901

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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