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C17orf71

SMG8 nonsense mediated mRNA decay factor

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.

Gene Name: SMG8 nonsense mediated mRNA decay factor
Synonyms: SMG8, C17orf71, ABC2, Protein SMG8, Protein smg-8 homolog
Target Sequences: NM_018149 NP_060619.4 Q8ND04

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Products
Antibodies (8)
Primary (8)
C17orf71 (8)
Human (8)
Mouse (4)
Rat (3)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (3)
IHC-P (1)
WB (4)
ELISA (1)
IP (1)
rabbit (8)
IgG (4)
polyclonal pc (8)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (5)
aa575-624 (4)
aa250-300 (2)
No (8)
C17orf71 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using SMG8 Polyclonal Antibody at dilution of 1:50.
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C17orf71 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
C17orf71 Antibody - Detection of Human ABC2 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:1000 (1 ug/ml).
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C17orf71 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Human
IHC, IP
Unconjugated
10 µg/$295; 100 µl/$493
C17orf71 Antibody - Detection of Human ABC2 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:250.
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C17orf71 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$510
C17orf71 Antibody - C17orf71 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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C17orf71 Rabbit anti-Human Polyclonal (aa575-624) Antibody
Human
WB
Unconjugated
100 µl/$424
C17orf71 Antibody - C17orf71 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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C17orf71 Rabbit anti-Human Polyclonal (aa575-624) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
C17orf71 Antibody - C17orf71 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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C17orf71 Rabbit anti-Human Polyclonal (aa575-624) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
C17orf71 Antibody - C17orf71 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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C17orf71 Rabbit anti-Human Polyclonal (aa575-624) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
C17orf71 Antibody - Immunochemical staining of human C17orf71 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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C17orf71 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).