C14orf169 / NO66

chromosome 14 open reading frame 169

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation By similarity. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation.

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Products

Antibodies (13)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (13)

Recombinant (1)

Target

C14orf169 / NO66 (16)

Reactivity

Human (13)

Mouse (3)

Rat (3)

Bovine (1)

Chimpanzee (3)

Dog (1)

Hamster (1)

Horse (1)

Monkey (4)

Pig (4)

Application

IHC (2)

WB (10)

DB (2)

ELISA (3)

IP (2)

Peptide-ELISA (1)

Host

rabbit (9)

mouse (3)

goat (1)

Isotype

IgG (9)

IgG1 (3)

Clonality

monoclonal mc (3)

polyclonal pc (10)

Clone

3354C5a (2)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (10)

Epitope

aa67-116 (4)

aa1-50 (1)

aa463-473 (1)

aa50-100 (1)

Publications

No (16)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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C14orf169 / NO66 Antibody (aa50-100) LS-C289895

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal (aa50-100) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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C14orf169 / NO66 Antibody LS-C829945

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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C14orf169 / NO66 Antibody LS-C831173

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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C14orf169 / NO66 Antibody LS-C754262

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

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C14orf169 / NO66 Antibody (clone 3354C5a) LS-C342540

Antibody:

C14orf169 / NO66 Mouse anti-Human Monoclonal (3354C5a) Antibody

Reactivity:

Human

Applications:

DB, WB

Format:

Unconjugated

Price:

100 µg/$486

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C14orf169 / NO66 Antibody (aa1-50) LS-C289894

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

C14orf169 / NO66 Antibody (aa463-473) LS-C61715

Antibody:

C14orf169 / NO66 Goat anti-Human Polyclonal (aa463-473) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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C14orf169 / NO66 Antibody LS-C79316

Antibody:

C14orf169 / NO66 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$558

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C14orf169 / NO66 Antibody (clone 3354C5a) LS-C184499

Antibody:

C14orf169 / NO66 Mouse anti-Human Monoclonal (3354C5a) Antibody

Reactivity:

Human

Applications:

DB

Format:

Unconjugated

Price:

100 µg/$965

Select

C14orf169 / NO66 Antibody (aa67-116) LS-C31355

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal (aa67-116) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

C14orf169 / NO66 Antibody (aa67-116, HRP) LS-C429812

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal (aa67-116) (HRP) Antibody

Reactivity:

Pig, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

C14orf169 / NO66 Antibody (aa67-116, Biotin) LS-C429811

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal (aa67-116) (Biotin) Antibody

Reactivity:

Pig, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

C14orf169 / NO66 Antibody (aa67-116, FITC) LS-C429810

Antibody:

C14orf169 / NO66 Rabbit anti-Human Polyclonal (aa67-116) (FITC) Antibody

Reactivity:

Pig, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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C14orf169 / NO66 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109785

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71.1 kDa

Price:

100 µg/$494

Select

Human C14orf169 / NO66 Protein (Recombinant GST) (Full Length) - LS-G35249

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

97.5 kDa

Price:

2 µg/$439

Select

Human C14orf169 / NO66 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91789

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71.1 kDa

Price:

20 µg/$150

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