c-Src Kinase / CSK

c-src tyrosine kinase

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

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Products

Proteins (17)

Type

Over-Expression Lysate (5)

Recombinant (12)

Target

c-Src Kinase / CSK (17)

Publications

No (17)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (2)

His (1)

His-GST (3)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (12)

Mouse (3)

Source

293T Cells (2)

Baculovirus (3)

E. coli (3)

HEK 293 Cells (5)

Insect Cells (2)

Wheat Germ Extract (2)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (5)

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Human c-Src Kinase / CSK Protein (Recombinant 6His, N-terminus) (Ser2-Leu450) - LS-G26650

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

50 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human c-Src Kinase / CSK Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67234

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

20 µg/$1,107

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Human c-Src Kinase / CSK Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67235

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

20 µg/$1,107

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Human c-Src Kinase / CSK Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G58239

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human c-Src Kinase / CSK Protein (Recombinant His-T7) (aa243-438) - LS-G24794

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.8 kDa

Price:

10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646

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Human c-Src Kinase / CSK Protein (Recombinant GST) (Full Length) - LS-G28061

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.13 kDa

Price:

10 µg/$479; 25 µg/$670

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Human c-Src Kinase / CSK Protein (Over-Expression Lysate 6His, N-terminus) (Ser2-Leu450) - LS-G26770

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

50 kDa

Price:

100 µg/$298

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c-Src Kinase / CSK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100279

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

100 µg/$494

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Human c-Src Kinase / CSK Protein (Recombinant GST, N-terminus) (Met1-Leu450) - LS-G140003

Source:

Insect Cells

Tag:

GST, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

77 kDa

Price:

50 µg/$707

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Mouse c-Src Kinase / CSK Protein (Recombinant) (Met1-Leu450) - LS-G140017

Source:

Insect Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.9 kDa

Price:

50 µg/$625

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c-Src Kinase / CSK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124552

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

100 µg/$494

Select

Human c-Src Kinase / CSK Protein (Recombinant His) - LS-G3060

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Human c-Src Kinase / CSK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79392

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

20 µg/$150

Select

Human c-Src Kinase / CSK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79393

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

20 µg/$150

Select

Human c-Src Kinase / CSK Protein (Recombinant His-GST) (Met1-Leu536) - LS-G97917

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

87.7 kDa

Price:

50 µg/$707

Select

Mouse c-Src Kinase / CSK Protein (Recombinant His-GST) (Met1-Leu535) - LS-G98285

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

87.7 kDa

Price:

50 µg/$707

Select

Mouse c-Src Kinase / CSK Protein (Recombinant His-GST) (Met1-Leu450) - LS-G98747

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

78.5 kDa

Price:

50 µg/$707

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