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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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c-Src Kinase / CSK

c-src tyrosine kinase

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

Gene Name: c-src tyrosine kinase
Family/Subfamily: Protein Kinase , Csk
Synonyms: CSK, C-src tyrosine kinase, C-Src kinase, Protein-tyrosine kinase CYL, Tyrosine-protein kinase CSK, C-SRC, Cytoplasmic tyrosine kinase
Target Sequences: NM_004383 NP_004374.1 P41240

Filtered By: None
Target
c-Src Kinase / CSK (76)
Reactivity
Human (73)
Mouse (39)
Rat (22)
Bat (5)
Bovine (7)
Chicken (6)
Chimpanzee (3)
Dog (7)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (5)
Monkey (6)
Pig (6)
Zebrafish (5)
Application
IHC (20)
IHC-P (6)
WB (75)
Flo (1)
ELISA (22)
ICC (6)
IF (6)
IP (6)
Peptide-ELISA (7)
RNAi (1)
Host
rabbit (60)
mouse (8)
goat (8)
Isotype
IgG (46)
IgG1 (4)
IgG1,k (1)
IgG2b,k (1)
Clonality
monoclonal mc (9)
polyclonal pc (67)
Clone
3A3 (1)
5F3 (1)
AT7C6 (1)
CSK-04 (2)
Format
AP Conjugated (4)
APC (1)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (8)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (6)
PE Conjugated (5)
Unconjugated (40)
Epitope
aa243-438 (10)
aa33-61 (8)
aa377-404 (8)
aa323-372 (4)
aa330-450 (3)
pSer364 (3)
300-380 aa (2)
1-80 aa, N-terminal (1)
Asn63 (1)
C-Terminus (1)
Leu558 (1)
N-Terminus (1)
Val399 (1)
aa164-197 (1)
aa17-51 (1)
aa2-204 (1)
aa31-80 (1)
aa330-379 (1)
aa375-425 (1)
aa398-431 (1)
aa400-450 (1)
aa438-450 (1)
aa67-101 (1)
Publications
No (76)
Showing 1-25 of 76 results

c-Src Kinase / CSK Antibody (aa400-450) IHC-plus™ LS-B14204
Rabbit Polyclonal to Human c-Src Kinase / CSK
Mouse, Dog, Pig, Human, Monkey
IHC IHC-P IP WB
Unconjugated
50µl 1mg/ml  $425.00
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Human and Mouse CSK by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-CSK antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Human and Mouse CSK by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-CSK antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

c-Src Kinase / CSK Antibody (aa377-404, Azide-free, HRP) LS-C255517
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Human
ELISA WB
HRP Conjugated, Azide-free
200µl 0.5mg/ml  $680.00

c-Src Kinase / CSK Antibody (Val399) LS-C63922
Rabbit Monoclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Rat, Human
WB
Unconjugated
100µl  $530.00

c-Src Kinase / CSK Antibody (aa375-425) IHC-plus™ LS-B14203
Rabbit Polyclonal to Human c-Src Kinase / CSK
Chicken, Bovine, Mouse, Dog, Rat, Horse, Human
IHC IHC-P IP
Unconjugated
50µl 1mg/ml  $425.00
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

c-Src Kinase / CSK Antibody (clone 5F3) LS-C169267
Mouse Monoclonal [clone 5F3] (IgG1) to Human c-Src Kinase / CSK
Human
ELISA Flo IF WB
Unconjugated
100µl  $345.00
Immunofluorescence of U251 cells using CSK mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Western blot using CSK mouse monoclonal antibody against NIH/3T3 (1),HeLa (2),COS7 (3), Jurkat (4), Raw246.7 (5), A549 (6), HL-60 (7) and PC-12 (8) cell lysate.
Immunofluorescence of U251 cells using CSK mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Western blot using CSK mouse monoclonal antibody against NIH/3T3 (1),HeLa (2),COS7 (3), Jurkat (4), Raw246.7 (5), A549 (6), HL-60 (7) and PC-12 (8) cell lysate.

c-Src Kinase / CSK Antibody LS-C664822
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $335.00

c-Src Kinase / CSK Antibody (clone 3A3) LS-C133138
Mouse Monoclonal [clone 3A3] (IgG1,k) to Human c-Src Kinase / CSK
Human
ELISA IP RNAi WB
Unconjugated
100µg  $355.00
CSK monoclonal antibody (M01), clone 3A3 Western blot of CSK expression in HL-60.
CSK monoclonal antibody (M01), clone 3A3. Western blot of CSK expression in HeLa NE.
CSK monoclonal antibody (M01), clone 3A3 Western blot of CSK expression in HL-60.
CSK monoclonal antibody (M01), clone 3A3. Western blot of CSK expression in HeLa NE.

c-Src Kinase / CSK Antibody LS-C664823
Mouse Monoclonal (IgG1) to Human c-Src Kinase / CSK
Human
ELISA IF WB
Unconjugated
100µg  $335.00

c-Src Kinase / CSK Antibody (1-80 aa, N-terminal) LS-C382925
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Rat, Human
ELISA IF WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Csk antibody
Western blot of Csk antibody

c-Src Kinase / CSK Antibody (clone AT7C6) LS-C755438
Mouse Monoclonal [clone AT7C6] (IgG2b,k) to Human c-Src Kinase / CSK
Human
ELISA ICC WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $315.00
ICC/IF analysis of CSK in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CSK antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CSK antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: 293T cell lysate Lane 2.: CSK transfected 293T cell lysate
ICC/IF analysis of CSK in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CSK antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CSK antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: 293T cell lysate Lane 2.: CSK transfected 293T cell lysate

c-Src Kinase / CSK Antibody (300-380 aa) LS-C380896
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Phospho-Csk (S364) antibody
Western blot of Phospho-Csk (S364) antibody

c-Src Kinase / CSK Antibody (300-380 aa) LS-C382924
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Csk antibody
Western blot of Csk antibody
Western blot of Csk antibody
Western blot of Csk antibody

c-Src Kinase / CSK Antibody (aa330-450, clone CSK-04) LS-C46038
Mouse Monoclonal [clone CSK-04] (IgG1) to Human c-Src Kinase / CSK
Mouse, Human
ICC IP WB
Unconjugated
100µl  $290.00
Immunofluorescence staining of Csk in human HeLa cell line using anti-Csk (CSK-04; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue).
Immunofluorescence staining of Csk in human HeLa cell line using anti-Csk (CSK-04; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue).
Immunofluorescence staining of Csk in human HeLa cell line using anti-Csk (CSK-04; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue).
Immunofluorescence staining of Csk in human HeLa cell line using anti-Csk (CSK-04; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue).

c-Src Kinase / CSK Antibody (aa330-450) LS-C355574
Rabbit Polyclonal to Human c-Src Kinase / CSK
Human
IHC IHC-P WB
Unconjugated
100µg  $345.00

c-Src Kinase / CSK Antibody (aa31-80) LS-C118888
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Rat, Human
IF Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunofluorescence analysis of A549 cells, using CSK Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from Jurkat cells, using CSK Antibody. The lane on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of A549 cells, using CSK Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from Jurkat cells, using CSK Antibody. The lane on the right is blocked with the synthesized peptide.

c-Src Kinase / CSK Antibody (aa2-204) LS-C343964
Rabbit Polyclonal to Human c-Src Kinase / CSK
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $325.00
CSK antibody Western blot. All lanes: Anti CSK at 0.5 ug/ml. WB: Recombinant Human CSK Protein 0.5ng. Predicted band size: 47 kD. Observed band size: 47 kD.
CSK antibody Western blot. All lanes: Anti CSK at 0.5 ug/ml. WB: Recombinant Human CSK Protein 0.5ng. Predicted band size: 47 kD. Observed band size: 47 kD.

c-Src Kinase / CSK Antibody (aa330-379) LS-C117597
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Mouse, Rat, Human
IHC Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CSK Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from Raw264.7 cells, treated with UV 5', using CSK Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CSK Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from Raw264.7 cells, treated with UV 5', using CSK Antibody. The lane on the right is blocked with the synthesized peptide.

c-Src Kinase / CSK Antibody (Leu558) LS-C176592
Rabbit Polyclonal to Human c-Src Kinase / CSK
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µl  $345.00
IHC of Csk (L558) pAb in paraffin-embedded human breast carcinoma tissue.
Western blot of Csk (L558) pAb in extracts from Raw264.7 cells.
IHC of Csk (L558) pAb in paraffin-embedded human breast carcinoma tissue.
Western blot of Csk (L558) pAb in extracts from Raw264.7 cells.

c-Src Kinase / CSK Antibody LS-C342022
Mouse Monoclonal to Human c-Src Kinase / CSK
Rat, Human
ICC WB
Unconjugated
100µl 1mg/ml  $385.00

c-Src Kinase / CSK Antibody (aa67-101) LS-C344400
Rabbit Polyclonal to Human c-Src Kinase / CSK
Mouse
IHC IHC-P WB
Unconjugated
400µl  $305.00
Immunohistochemical of paraffin-embedded M.spleen section using Mouse Csk Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Western blot of lysate from mouse liver tissue lysate with Mouse Csk Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.
Immunohistochemical of paraffin-embedded M.spleen section using Mouse Csk Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Western blot of lysate from mouse liver tissue lysate with Mouse Csk Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

c-Src Kinase / CSK Antibody (aa438-450) LS-C20150
Goat Polyclonal to Human c-Src Kinase / CSK
Mouse, Dog, Pig, Bat, Human
IHC Peptide-ELISA WB
Unconjugated
100µg 0.5mg/ml  $405.00
Staining (0.5 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
Staining (0.5 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

c-Src Kinase / CSK Antibody (Asn63) LS-C176908
Rabbit Polyclonal to Human c-Src Kinase / CSK
Mouse, Rat, Human
IF WB
Unconjugated
100µl  $345.00
Western blot of Csk (N63) pAb in extracts from HepG2 cells.
Western blot of Csk (N63) pAb in extracts from HepG2 cells.

c-Src Kinase / CSK Antibody LS-C485684
Rabbit Polyclonal to Mouse c-Src Kinase / CSK
Mouse
ELISA WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

c-Src Kinase / CSK Antibody LS-C393568
Mouse Monoclonal to Human c-Src Kinase / CSK
Human
ICC WB
Unconjugated
100µl  $305.00
Immunocytochemistry staining of C6 cells fixed by anhydrous methanol for 2 h at -20°C and using anti-CSK mouse monoclonal antibody (dilution 1:50).
Western blot detection of CSK in C6 and Jurkat cell lysates using CSK mouse monoclonal antibody (1:1000 dilution). Predicted band size: 50KDa. Observed band size:50KDa.
Immunocytochemistry staining of C6 cells fixed by anhydrous methanol for 2 h at -20°C and using anti-CSK mouse monoclonal antibody (dilution 1:50).
Western blot detection of CSK in C6 and Jurkat cell lysates using CSK mouse monoclonal antibody (1:1000 dilution). Predicted band size: 50KDa. Observed band size:50KDa.

c-Src Kinase / CSK Antibody (aa243-438) LS-C374446
Rabbit Polyclonal (IgG) to Human c-Src Kinase / CSK
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of c-Src Kinase / CSK antibody.
Western blot of c-Src Kinase / CSK antibody.
Showing 1-25 of 76 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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