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Unfortunately, the antibody (ID:156225) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



c-Kit / CD117

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.

Gene Name: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Family/Subfamily: Protein Kinase , PDGF Receptor
Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen
Target Sequences: NM_000222 NP_000213.1 P10721

Filtered By: None
Target
c-kit-cd117 (553)
Reactivity
Human (445)
Mouse (140)
Rat (19)
Bat (1)
Bovine (12)
Chicken (6)
Cynomolgus monkey (2)
Dog (7)
Goat (4)
Horse (4)
Monkey (12)
Pig (6)
Primate (12)
Rabbit (3)
Application
IHC (104)
IHC-Fr (10)
IHC-P (34)
WB (233)
Flo (129)
DB (160)
ELISA (282)
Func (4)
ICC (5)
IF (42)
IP (29)
Neut (6)
Peptide-ELISA (8)
Host
rabbit (393)
mouse (103)
goat (1)
rat (56)
Isotype
IgG (330)
IgG1 (47)
IgG1,k (12)
IgG2a (30)
IgG2a,k (1)
IgG2b (39)
IgG2b,k (19)
IgM (2)
Clonality
monoclonal mc (162)
polyclonal pc (391)
Clone
104D2 (7)
12A8 (1)
1C5 (1)
1E2 (1)
1F6 (1)
2B5 (1)
2B8 (29)
2B8/BM (1)
2C1 (2)
2c75 (4)
2E3 (1)
3C1 (4)
3F9 (1)
4F7 (1)
57A5 (6)
5F6 (1)
6G12 (1)
8D7 (1)
8D7B4, 8D7D4, 7H6B2, 7H6B12 (2)
9A11 (1)
A3C6E2 (2)
A4 (1)
ACK2 (5)
ACK4 (4)
C117/370 (2)
C117/370 + KIT/982 + KIT/983 (2)
CLDA117 (2)
K45 (2)
KIT/982 (2)
KIT/983 (2)
NU-c-kit (3)
SP26 (1)
T595 (1)
X1 (1)
YB5.B8 (4)
YR145 (1)
Format
AP Conjugated (48)
APC (3)
APC Conjugated (54)
Azide-free (45)
Biotin Conjugated (60)
Cy5 Conjugated (5)
Cy5.5 Conjugated (1)
Cy7 Conjugated (5)
FITC Conjugated (62)
HRP Conjugated (50)
Low Endotoxin (1)
PE (5)
PE Conjugated (64)
Ready-to-Use (1)
RPE Conjugated (3)
SPRD Conjugated (2)
Unconjugated (199)
Epitope
pTyr936 (15)
pTyr719 (9)
pTyr730 (9)
Tyr703 (8)
aa252-281 (8)
aa334-361 (8)
aa340-369 (8)
aa527-553 (8)
aa547-577 (8)
aa556-585 (8)
aa691-720 (8)
aa708-737 (8)
aa724-753 (8)
aa807-836 (8)
aa878-905 (8)
aa9-40 (8)
aa914-941 (8)
aa937-966 (8)
pSer716 (8)
pSer739 (8)
pSer746 (8)
pSer821 (8)
pSer891 (8)
pSer959 (8)
pThr274 (8)
pThr354 (8)
pThr357 (8)
pThr718 (8)
pTyr362 (8)
pTyr547 (8)
pTyr553 (8)
pTyr570 (8)
pTyr578 (8)
pTyr823 (8)
pTyr900 (8)
aa100-300 (6)
pTyr721 (6)
Internal (5)
C-Terminus (4)
aa546-976 (4)
N-Terminus (3)
aa321-520 (3)
aa343-527 (3)
aa912-941 (3)
pTyr703 (3)
Cytoplasmic Domain (2)
Extracellular Domain (2)
Glu930 (1)
Ser715 (1)
aa1-976 (1)
aa26-285 (1)
aa336-367 (1)
aa660-740 (1)
aa685-697 (1)
aa688-737 (1)
aa719-723 (1)
aa880-960 (1)
aa881-930 (1)
aa906-955 (1)
aa925-976 (1)
aa934-938 (1)
Publications
No (552)
Yes (1)
Showing 1-25 out of 553 results
Anti-c-Kit / CD117 Antibody (Extracellular Domain) IHC-plus™ LS-A9389
Anti-c-Kit antibody LS-A9389 IHC of human spleen, central artery and lymphocytes within periarteriolar lymphoid sheaths. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Rabbit Polyclonal to Human c-Kit / CD117
Human
IHC IHC-P
Unconjugated
Anti-c-Kit / CD117 Antibody (clone X1) IHC-plus™ LS-B6060
Anti-c-Kit antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6060 concentration 2.5 ug/ml.

Mouse Monoclonal [clone X1] (IgG2b,k) to Human c-Kit / CD117
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody LS-C78828
Immunofluorescence staining of rat skin (epidermis). c-KIT detection was done using LS-C78828 (red color). DAPI was used to counterstain cell nuclei (blue color). Working dilution: 1:100-1:300.

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Rat, Human
Flo IF IHC
Unconjugated
Anti-c-Kit / CD117 Antibody (clone ACK2) LS-C107133

Rat Monoclonal [clone ACK2] (IgG2b,k) to Mouse c-Kit / CD117
Mouse
Flo IHC IHC-Fr IP
Unconjugated
Anti-c-Kit / CD117 Antibody (clone NU-c-kit, FITC) LS-C140410

Mouse Monoclonal [clone NU-c-kit] (IgG) to Human c-Kit / CD117
Human
Flo
FITC Conjugated
Anti-c-Kit / CD117 Antibody (Cytoplasmic Domain) IHC-plus™ LS-B5194
Anti-c-Kit antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5194 dilution 1:50.

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Dog, Human
IHC IHC-P
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 4F7) IHC-plus™ LS-B6059
Anti-c-Kit antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6059 concentration 2.5 ug/ml.

Mouse Monoclonal [clone 4F7] (IgG) to Human c-Kit / CD117
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 6G12) IHC-plus™ LS-B6057
Anti-c-Kit antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6057 concentration 2.5 ug/ml.
Detection limit for recombinant GST tagged KIT is 0.03 ng/ml as a capture antibody.

Mouse Monoclonal [clone 6G12] (IgG2b,k) to Human c-Kit / CD117
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone ACK4) LS-C34582

Rat Monoclonal [clone ACK4] (IgG2a) to Mouse c-Kit / CD117
Mouse
Flo IHC IHC-Fr
Unconjugated
Anti-c-Kit / CD117 Antibody (clone K45) LS-C88025
Frozen human tonsil section stained UltraVision LP and AEC chromogen. Note staining of mast cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.

Mouse Monoclonal [clone K45] (IgG2a) to Human c-Kit / CD117
Human
IF IHC IHC-Fr
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 104D2) LS-C40873
Human myeloid cell line TF-1 stained with purified 104D2, followed by biotinylated anti-mouse IgGs and Sav-PE

Mouse Monoclonal [clone 104D2] (IgG1) to Human c-Kit / CD117
Bovine, Human, Monkey
Flo IF IP
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 5F6) IHC-plus™ LS-B6058
Anti-c-Kit antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6058 concentration 2.5 ug/ml.
Western blot of KIT expression in transfected 293T cell line by KIT monoclonal antibody, clone 5F6.

Mouse Monoclonal [clone 5F6] (IgG2b,k) to Human c-Kit / CD117
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (phospho-Ser959, PE) LS-C261310

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Human
DB ELISA
PE Conjugated
Anti-c-Kit / CD117 Antibody (clone ACK2, PE, Cy7) LS-C107226
Staining of C57Bl/6 bone marrow cells with FITC anti-mo/hu B220 (RA3-6B2) (LS-C105879) and 0.5 ug of PE-Cy7 Rat IgG2b isotype control. Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of C57Bl/6 bone marrow cells with FITC anti-mo/hu B220 (RA3-6B2) (LS-C105879) and 0.5 ug of PE-Cy7 anti-mouse CD117 (ACK2). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rat Monoclonal [clone ACK2] (IgG2b,k) to Mouse c-Kit / CD117
Mouse
Flo
PE, Cy7 Conjugated
Anti-c-Kit / CD117 Antibody (FITC) LS-C14157

Mouse Monoclonal (IgG1) to Human c-Kit / CD117
Human
Flo
FITC Conjugated
Anti-c-Kit / CD117 Antibody (aa912-941, PE) LS-C282542

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Mouse, Human
ELISA Flo IF IHC WB
PE Conjugated
Anti-c-Kit / CD117 Antibody (aa9-40) LS-C97561
Purified rabbit anti-KIT antibody was used in immunohistochemistry on Breast Carcinoma.
The anti-KIT antibody is used in Western blot to detect KIT in serum-starved HeLa cell lysate (lane 1) and primate testis tissue lysate (lane 2).

Rabbit Polyclonal to Human c-Kit / CD117
Human, Primate
Flo IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 2B8/BM) LS-C187513

Mouse Monoclonal [clone 2B8/BM] (IgG1) to Pig c-Kit / CD117
Pig
Flo IHC IHC-Fr IP WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 2C1) LS-C175534
IHC of paraffin-embedded Human colon tissue using anti-KIT mouse monoclonal antibody.
IHC of paraffin-embedded Human lymph node tissue using anti-KIT mouse monoclonal antibody.

Mouse Monoclonal [clone 2C1] (IgG1) to Human c-Kit / CD117
Human
IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (Cytoplasmic Domain, clone SP26) LS-C210616
Immunohistochemistry of Human Gastrointestinal Stromal Tumor stained with anti-CD117/c-kit antibody
Immunohistochemistry of Human Melanoma stained with anti-CD117/c-kit antibody

Rabbit Monoclonal [clone SP26] (IgG) to Human c-Kit / CD117
Human
IHC IHC-P
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 9A11) IHC-plus™ LS-B10212
IHC of paraffin-embedded Human lymph node tissue using anti-KIT mouse monoclonal antibody.
Anti-c-Kit / CD117 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10212 concentration 10 ug/ml.

Mouse Monoclonal [clone 9A11] (IgG2a) to Human c-Kit / CD117
Human
IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (phospho-Tyr936) LS-C205314
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using c-kit (Phospho-Tyr936) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot of extracts from C6 cell untreated or treated with serum using c-kit (phospho-Tyr936) antibody.

Rabbit Polyclonal to Human c-Kit / CD117
Human
IHC IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (Ser715) LS-C177669
Western blot of c-Kit (S715)pAb in extracts from A549 cells.

Rabbit Polyclonal to Human c-Kit / CD117
Mouse, Rat, Human
IF WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone YR145) LS-C202814

Rabbit Monoclonal [clone YR145] (IgG) to Human c-Kit / CD117
Human
IHC IHC-Fr IHC-P
Unconjugated
Anti-c-Kit / CD117 Antibody (clone A3C6E2) LS-C179621
Immunoprecipitation Image

Mouse Monoclonal [clone A3C6E2] (IgG1) to Human c-Kit / CD117
Human
Flo IP
Unconjugated

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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