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C/EBP Beta / CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes.
| Gene Name: | CCAAT/enhancer binding protein (C/EBP), beta |
| Synonyms: | CEBPB, C/EBP-beta, C/EBP beta, CRP2, LAP, Liver activator protein, Nuclear factor NF-IL6, IL6DBP, TCF5, NFIL6, TCF-5, Transcription factor 5, NF-IL6 |
| Target Sequences: | NM_005194 NP_005185.2 P17676 |
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