BRUCE / BIRC6

baculoviral IAP repeat containing 6

Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

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Products

ELISA Kits (3)

Type

Custom (1)

Sandwich (2)

Target

BRUCE / BIRC6 (3)

Reactivity

Human (3)

Format

96-Well Strip Plate (3)

Publications

No (3)

Sample Type

Cell Lysates (1)

Plasma (1)

Serum (1)

Tissue Homogenates (2)

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Human BRUCE / BIRC6 (Sandwich ELISA) ELISA Kit - LS-F8445

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Human BRUCE / BIRC6 (Sandwich ELISA) ELISA Kit - LS-F33886

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human BRUCE / BIRC6 (Custom ELISA) ELISA Kit - LS-F14259

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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