BRD8

bromodomain containing 8

May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

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Products

Antibodies (29)

Type

Primary (29)

Target

BRD8 (29)

Reactivity

Human (21)

Mouse (9)

Gibbon (3)

Orangutan (3)

Rabbit (3)

Application

IHC (9)

IHC-P (5)

WB (17)

ELISA (9)

IF (5)

IP (3)

Peptide-ELISA (1)

Host

rabbit (21)

mouse (8)

Product Group

IHCPlus (1)

Isotype

IgG (10)

IgG1 (1)

IgG2b,k (6)

Clonality

monoclonal mc (8)

polyclonal pc (21)

Format

APC (1)

APC Conjugated (2)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (11)

Epitope

aa797-951 (8)

aa539-588 (4)

aa225-275 of isoform 2 (2)

aa25-75 in Uniprot entry Q9H0E9.2) (1)

aa33-128 (1)

Publications

No (29)

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BRD8 Antibody (aa539-588) LS-B10257

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa539-588) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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BRD8 Antibody (aa539-588, HRP) LS-C430544

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa539-588) (HRP) Antibody

Reactivity:

Rabbit, Human, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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BRD8 Antibody (aa539-588, Biotin) LS-C430542

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa539-588) (Biotin) Antibody

Reactivity:

Rabbit, Human, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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BRD8 Antibody (aa539-588, FITC) LS-C430543

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa539-588) (FITC) Antibody

Reactivity:

Rabbit, Human, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BRD8 Antibody (aa25-75 in Uniprot entry Q9H0E9.2)) LS-C287136

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa25-75 in Uniprot entry Q9H0E9.2)) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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BRD8 Antibody (aa33-128) LS-C306566

Antibody:

BRD8 Mouse anti-Human Monoclonal (aa33-128) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$705

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BRD8 Antibody (HRP) LS-C541121

Antibody:

BRD8 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

100 µl/$904

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BRD8 Antibody (Biotin) LS-C520987

Antibody:

BRD8 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

BRD8 Antibody (FITC) LS-C531031

Antibody:

BRD8 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

FITC Conjugated

Price:

100 µl/$904

Select

BRD8 Antibody (PE) LS-C649231

Antibody:

BRD8 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

PE Conjugated

Price:

100 µl/$904

Select

BRD8 Antibody (APC) LS-C512773

Antibody:

BRD8 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

BRD8 Antibody (aa225-275 of isoform 2) LS-C287137

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa225-275 of isoform 2) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

BRD8 Antibody LS-C660016

Antibody:

BRD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

BRD8 Antibody LS-C671601

Antibody:

BRD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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BRD8 Antibody LS-C660018

Antibody:

BRD8 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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BRD8 Antibody LS-C835177

Antibody:

BRD8 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

3 ml/$277; 100 µl/$301; 6 ml/$329; 200 µl/$367

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BRD8 Antibody LS-C808965

Antibody:

BRD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BRD8 Antibody (aa225-275 of isoform 2) LS-C286296

Antibody:

BRD8 Rabbit anti-Human Polyclonal (aa225-275 of isoform 2) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

BRD8 Antibody (aa797-951) LS-C374373

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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BRD8 Antibody (aa797-951, HRP) LS-C711256

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

BRD8 Antibody (aa797-951, Biotin) LS-C686908

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

BRD8 Antibody (aa797-951, FITC) LS-C693685

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

Select

BRD8 Antibody (aa797-951, APC, Cy7) LS-C734278

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

Select

BRD8 Antibody (aa797-951, Cy3) LS-C702234

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

BRD8 Antibody (aa797-951, APC) LS-C717678

Antibody:

BRD8 Rabbit anti-Mouse Polyclonal (aa797-951) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• Cy3
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • Cy3
  • APC

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