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BRD7

bromodomain containing 7

Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.

Gene Name: bromodomain containing 7
Synonyms: BRD7, 75 kDa bromodomain protein, BP75, Bromodomain containing 7, Bromodomain-containing 7, CELTIX1, NAG4, Protein CELTIX-1
Target Sequences: NM_013263 NP_037395.2 Q9NPI1

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Products
Antibodies (25)
Primary (25)
BRD7 (25)
Human (24)
Mouse (10)
Rat (1)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Orangutan (3)
IHC (11)
IHC-P (8)
WB (19)
ELISA (13)
IF (2)
Peptide-ELISA (1)
rabbit (25)
Product Group
IHCPlus (1)
IgG (17)
polyclonal pc (25)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
aa77-106 (7)
C-Terminus (4)
aa601-651 (2)
aa387-418 (1)
No (25)
BRD7 Antibody - Anti-BRD7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BRD7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
BRD7 Antibody - Anti-BRD7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BRD7 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Dog, Human, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
BRD7 Antibody - Anti-BRD7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BRD7 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Dog, Human, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
BRD7 Antibody - Anti-BRD7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BRD7 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Dog, Human, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
BRD7 Antibody - Western blot of lysate from mouse lung tissue lysate with MOUSE Brd7 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35 ug.
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BRD7 Rabbit anti-Mouse Polyclonal (aa387-418) Antibody
Mouse
WB
Unconjugated
400 µl/$393
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
BRD7 Antibody - Immunohistochemistry - Anti-BRD7 Picoband antibody
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BRD7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BRD7 Antibody - Paraffin-embedding Immunohistochemistry using human lung cancer at dilution 1:100
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BRD7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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BRD7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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BRD7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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BRD7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
BRD7 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BRD7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BRD7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
BRD7 Antibody - Detection of Human BRD7 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD7 used at a dilution of 1:1000 (1 ug/ml).
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BRD7 Rabbit anti-Human Polyclonal (aa601-651) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µl/$295; 100 µl/$514
BRD7 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using BRD7 Polyclonal Antibody at dilution of 1:50(×200)
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BRD7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BRD7 Antibody - Detection of Human BRD7 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD7 used at a dilution of 1:250.
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BRD7 Rabbit anti-Human Polyclonal (aa601-651) Antibody
Human
IHC, IHC-P
Unconjugated
2.5 µg/$295; 100 µl/$532
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BRD7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$343; 120 µl/$427; 200 µl/$559
BRD7 Antibody - BRD7 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The BRD7 antibody detected the BRD7 protein (arrow).
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BRD7 Rabbit anti-Human Polyclonal (aa77-106) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
BRD7 Antibody - Western blot analysis of extracts of various cells.
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BRD7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
BRD7 Antibody
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BRD7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).