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BMPR2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Gene Name: bone morphogenetic protein receptor, type II (serine/threonine kinase)
Family/Subfamily: Protein Kinase , Activin/TGFb
Synonyms: BMPR2, BMPR-II, BMPR-2, BMPR3, BMP type II receptor, BRK-3, PPH1, T-ALK, BMP type-2 receptor, BMR2
Target Sequences: NM_001204 NP_001195.2 Q13873

Publications (2)

1
Binding of carbon nanotube to BMP receptor 2 enhances cell differentiation and inhibits apoptosis via regulating bHLH transcription factors. Zhang Y, Mu Q, Zhou H, Vrijens K, Roussel MF, Jiang G, Yan B. Cell death & disease. 2012 3:e308. [PubMed:22573038] [PMC:PMC3366082] Related Antibodies: LS-C97662.
2
Estradiol Upregulates the Expression of the TGF-ß Receptors ALK5 and BMPR2 during the Gonadal Development of Schizothorax prenanti. Taiming Yan, Songpei Zhang, Yueping Cai, Zhijun Ma, Jiayang He, Qian Zhang, Faqiang Deng, Lijuan Ye, Hongjun Chen, Liang He, Jie Luo, Deying Yang, Zhi He. Animals: an open access journal from MDPI. 2021 May;11: [Full Text Article] [PubMed:34064919] [PMC:PMC8151950] Related Antibodies: LS-C178875.

☰ Filters
Antibodies (44)
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BMPR2 (69)
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BMPR2 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BMPR2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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BMPR2 Rabbit anti-Human Polyclonal (aa28-59) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BMPR2 Antibody - Anti-BMPR2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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BMPR2 Mouse anti-Human Monoclonal (1F12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
BMPR2 Antibody - BMPR2 Antibody in Immunohistochemistry (IHC)
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BMPR2 Mouse anti-Human Monoclonal (3F6F8) Antibody
Mouse, Rat, Non-Human Primate, Human
Flo, ICC, IF, IHC-P, WB
Unconjugated
100 µg/$541
BMPR2 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded muscle tissues (left) and kidney cancer tissues (right) with DAB staining using BMPR-II Monoclonal Antibody.
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BMPR2 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
BMPR2 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded breast cancer tissues (left) and tonsil tissues (right) with DAB staining using BMPR-II Monoclonal Antibody.
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BMPR2 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
BMPR2 Antibody - Anti-BMPR2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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BMPR2 Mouse anti-Human Monoclonal (3F6) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
BMPR2 Antibody - BMPR2 Antibody in Immunohistochemistry (IHC)
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BMPR2 Mouse anti-Human Monoclonal (1F12) Antibody
Mouse, Rat, Non-Human Primate, Human
IHC, WB
Unconjugated
100 µl/$541
BMPR2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
BMPR2 Antibody
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BMPR2 Rabbit anti-Human Polyclonal (aa295-552) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
BMPR2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
BMPR2 ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
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BMPR2 Rabbit anti-Human Polyclonal (aa28-59) Antibody
Human
Flo, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$734
Select
BMPR2 Rabbit anti-Human Polyclonal (aa28-59) (Biotin) Antibody
Human
IHC-P, WB
Biotin Conjugated
200 µl/$952
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BMPR2 Rabbit anti-Human Polyclonal (aa28-59) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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BMPR2 Rabbit anti-Human Polyclonal (aa28-59) (PE) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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BMPR2 Rabbit anti-Human Polyclonal (aa28-59) (APC) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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BMPR2 Rabbit anti-Human Polyclonal (aa28-59) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
BMPR2 Antibody - Western blot analysis of extracts of various cell lines, using BMPR2 antibody.
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BMPR2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
BMPR2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
BMPR2 Antibody - Immunohistochemistry of paraffin-embedded Human placenta using BMPR2 Polyclonal Antibody at dilution of 1:100 (40x lens).
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BMPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BMPR2 Antibody - Western blot analysis of BMPR2 expression in H1299 whole cells lysate. The lane on the left is treated with the antigen-specific peptide.
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BMPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BMPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
BMPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
Select
BMPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
BMPR2 Antibody - Western blot - Anti-BMPR2/Bmpr Ii Picoband antibody
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BMPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 69 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).