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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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BMP4

bone morphogenetic protein 4

BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Gene Name: bone morphogenetic protein 4
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP4, BMP-2B, BMP-4, BMP2B, BMP2B1, Bone morphogenetic protein 2B, Bone morphogenetic protein 4, DVR4, MCOPS6, OFC11, Zyme
Target Sequences: NM_001202 NP_001193.2 P12644

Publications (1)

1
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM. Science immunology. 2018 January;3:pii: eaal2736. [Full Text Article] [PubMed:29330161] [PMC:PMC5795617]

Viewing 1-25 of 131 items
BMP4 Antibody - Anti-BMP4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Neuroscience
Rabbit Polyclonal (IgG) to Human BMP4
Xenopus, Chicken, Bovine, Rabbit, Mouse, Goat, Dog, Bat, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
BMP4 Antibody - Anti-BMP4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Neuroscience
Rabbit Polyclonal to Human BMP4
Chicken, Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µg   0.5mg/ml   $555.00
Select
Mouse Monoclonal [clone 3H2.3] (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
Unconjugated
100µg   1mg/ml   $665.00
Select
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
HRP Conjugated
100µl   $845.00
Select
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
Biotin Conjugated
100µl   $845.00
Select
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
FITC Conjugated
100µl   $845.00
Select
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
APC Conjugated
100µl   0.95mg/ml   $845.00
Select
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
AP Conjugated
100µl   $845.00
Select
Mouse Monoclonal (IgG2b) to Mouse BMP4
Mouse, Rat, Human
ELISA, ICC, WB
PE Conjugated
100µl   $845.00
BMP4 Antibody - Anti-BMP4 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal to Human BMP4
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
Select
Mouse Monoclonal (IgG2b) to Human BMP4
Human
ELISA, WB
Unconjugated
500µg   $255.00
BMP4 Antibody - Immunohistochemistry of paraffin-embedded Human brain using BMP4 Polyclonal Antibody at dilution of 1:25.
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Rabbit Polyclonal (IgG) to Human BMP4
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl   0.7mg/ml   $205.00; 60µl   0.7mg/ml   $235.00; 120µl   0.7mg/ml   $295.00; 200µl   0.7mg/ml   $395.00
BMP4 Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer tissue.
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Rabbit Polyclonal (IgG) to Human BMP4
Mouse, Rat
IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
BMP4 Antibody
Select
Rabbit Polyclonal (IgG) to Human BMP4
Human
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human BMP4
Human
ELISA, WB
HRP Conjugated
50µg   $285.00; 100µg   0.42mg/ml   $385.00
BMP4 Antibody - Immunohistochemical staining of paraffin-embedded human stomach carcinoma using BMP4 clone UMAB42, mouse monoclonal antibody at 1:100 dilution of 1mg/mL using Polink2 Broad HRP DAB for detection.requires heat-induced epitope retrieval with Accel pH8.7 at 110C for 3 min using pressure chamber/cooker. The image shows strong membranous and cytoplasmic staining.
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Mouse Monoclonal [clone UMAB42] (IgG1) to Human BMP4
Human
IF, IHC, PMA, WB
Unconjugated, Carrier-free
100µg   $425.00
BMP4 Antibody - Immunohistochemical staining of paraffin-embedded human stomach carcinoma using BMP4 clone UMAB42, mouse monoclonal antibody at 1:100 dilution of 1mg/mL using Polink2 Broad HRP DAB for detection.requires heat-induced epitope retrieval with Accel pH8.7 at 110C for 3 min using pressure chamber/cooker. The image shows strong membranous and cytoplasmic staining.
Select
Mouse Monoclonal [clone UMAB42] (IgG1) to Human BMP4
Human
IF, IHC, PMA, WB
Unconjugated
100µl   $395.00
BMP4 Antibody - Western blot of recombinant BMP4 / BMP-4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Cow BMP4
Mouse, Bovine, Rat, Cow, Human
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $315.00; 1ml   0.5mg/ml   $560.00
Select
Mouse Monoclonal to Human BMP4
Human
Flo, ICC, IF
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Select
Mouse Monoclonal [clone 3C11H8] (IgG1) to Human BMP4
Human
ELISA, IF, WB
Unconjugated
0.1mg   $365.00
Select
Rabbit Polyclonal (IgG) to Human BMP4
Human
ELISA, IHC, WB
Unconjugated
100µg   $405.00
BMP4 Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer using BMP4 antibody at dilution of 1:100 (40x lens).
Select
Rabbit Polyclonal (IgG) to Human BMP4
Mouse, Rat, Human
IF, IHC
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Mouse Monoclonal [clone 3C11C7] (IgG1) to Human BMP4
Human
ELISA, Flo
Unconjugated
0.1mg   $365.00
BMP4 Antibody
Select
Rabbit Polyclonal to Human BMP4
Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
BMP4 Antibody - Anti-BMP4 mouse monoclonal antibody  immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY BMP4.
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Mouse Monoclonal [clone OTI6B7] (IgG1) to Human BMP4
Human
IF, WB
Unconjugated, Carrier-free
100µg   $395.00

Viewing 1-25 of 131 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).