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BMP2

bone morphogenetic protein 2

BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein induces bone formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva.

Gene Name: bone morphogenetic protein 2
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP2, BDA2, BMP-2, BMP-2A, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
Target Sequences: NM_001200 NP_001191.1 P12643

Publications (7)

1
Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases. Handlogten ME, Huang C, Shiraishi N, Awata H, Miller RT. The Prostate. 2013 (IHC-P; Human) [PubMed:23334979]
2
Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters. Grunseich C, Wang IX, Watts JA, Burdick JT, Guber RD, Zhu Z, Bruzel A, Lanman T, Chen K, Schindler AB, Edwards N, Ray-Chaudhury A, Yao J, Lehky T, Piszczek G, Crain B, Fischbeck KH, Cheung VG. Molecular cell. 2018 February;69:426-437. [Full Text Article] [PubMed:29395064] [PMC:PMC5815878] Related Antibodies: LS-B12549.
3
Laminin differentially regulates the stemness of type I and type II pericytes. Gautam J, Nirwane A, Yao Y. Stem cell research & therapy. 2017 February;8:28. [Full Text Article] [PubMed:28173861] [PMC:PMC5297126]
4
Combination of bone morphogenetic protein-2 plasmid DNA with chemokine CXCL12 creates an additive effect on bone formation onset and volume. F Wegman, M T Poldervaart, Y J van der Helm, F C Oner, W J Dhert, J Alblas. European cells & materials. 2015 July;30:1-10; discussion 10-1. [Full Text Article] [PubMed:26214286]
5
Bone formation by heterodimers through non-viral gene delivery of BMP-2/6 and BMP-2/7. L D Loozen, A Vandersteen, A H Kragten, F C Öner, W J Dhert, M C Kruyt, J Alblas. The Breast : official journal of the European Society of Mastology. 2018 Mar;35:195-208. [Full Text Article] [PubMed:29589649]
6
BMP-2 gene delivery in cell-loaded and cell-free constructs for bone regeneration. Loek D Loozen, Moyo C Kruyt, Angela H M Kragten, Ted Schoenfeldt, Michiel Croes, Cumhur F Oner, Wouter J A Dhert , Jacqueline Alblas. PloS one. 2019 Jul;14:e0220028. [Full Text Article] [PubMed:31365542] [PMC:PMC6668905]
7
The promising effects of BMP2 transfected mesenchymal stem cells on human osteosarcoma. Ahmet Sinan Sari, Emre Demirçay, Ahmet Öztürk, Aysen Terzi, Erdal Karaöz. Turkish journal of biology = Tu¨rk biyoloji dergisi / the Scientific and Technical Research Council of Turkey. 2021 Jun;45:301-313. [Full Text Article] [PubMed:34377054] [PMC:PMC8313938] Related Antibodies: LS-B12549.
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☰ Filters
Products
Proteins (32)
Over-Expression Lysate (2)
Recombinant (30)
BMP2 (32)
Animal-free (1)
No (32)
6His-SUMO, N-terminus (1)
Fc, C-terminus (1)
GST (1)
GST, N-terminus (2)
His (8)
His, N-Terminal (1)
His-GST (1)
His-T7 (2)
Human Mutant IgG1 Fc (1)
Myc-DDK (Flag) (2)
Bovine (1)
Dog (2)
Human (23)
Mouse (1)
Pig (2)
Rabbit (1)
Rat (1)
293T Cells (1)
CHO Cells (2)
E. coli (24)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (8)
Low endotoxin level (12)
Biologically active (7)
Animal-free (1)
Select
E. coli
His
Less than 0.1 EU/µg protein (determined by LAL method).
50 µg/$587; 10 µg/$337
BMP2 Protein - Recombinant Bone Morphogenetic Protein 2 By SDS-PAGE
Select
E. coli
His-GST
44.6 kDa
10 µg/$280; 50 µg/$435; 100 µg/$695; 200 µg/$870; 1 mg/$1,972; 500 µg/$1,514; 5 mg/$3,039; 2 mg/$2,159
BMP2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
28.9 kDa
20 µg/$323; 1 mg/$1,355; 100 µg/$420
Select
CHO Cells
None
Biologically active
26 kDa or 28-29 kDa
10 µg/$349; 2 µg/$268
Select
E. coli
None
Less than 0.1 EU/µg protein (determined by LAL method).
13 kDa
20 µg/$677
BMP2 Protein
Select
E. coli
His, N-Terminal
42.4 kDa
50 µg/$419
BMP2 Protein - Biological Activity BMP-2, Human induce alkaline phosphatase production by C2C12 cells. The ED 50 for this effect is typically 0.10-0.80 ug/mL.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
26 kDa (SDS-PAGE)
50 µg/$470; 10 µg/$296; 1 mg/$2,064
BMP2 Protein - 12.5% SDS-PAGE of human BMP2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
70.51 kDa
2 µg/$439
Select
293T Cells
Myc-DDK (Flag)
44.63 kDa
20 µg/$150
BMP2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
BMP2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
HEK 293 Cells
Myc-DDK (Flag)
44.63 kDa
100 µg/$494
Select
CHO Cells
Human Mutant IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$498
Select
E. coli
None
Biologically active
26.0 kDa
10 µg/$388; 100 µg/$1,186; 500 µg/$2,269
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
26.0 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
BMP2 Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
250 µg/$739; 50 µg/$361
Select
E. coli
None
13 kDa
20 µg/$485; 100 µg/$918
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39.5 kDa
20 µg/$430; 100 µg/$907
BMP2 Protein
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.3 kDa
20 µg/$360; 100 µg/$728
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,815; 1 mg/$2,588
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~26 kDa
10 µg/$395; 1 mg/$6,427
BMP2 Protein - Recombinant Bone Morphogenetic Protein 2 By SDS-PAGE
Select
E. coli
His
16.7 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
BMP2 Protein - Recombinant Bone Morphogenetic Protein 2 By SDS-PAGE
Select
E. coli
His-T7
46.2 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Viewing 1-25 of 32 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).