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BMP15 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.
Gene Name: | bone morphogenetic protein 15 |
Family/Subfamily: | TGF beta , not assigned-TGF beta |
Synonyms: | BMP15, Bone morphogenetic protein 15, BMP-15, GDF9B, GDF-9B, ODG2, POF4 |
Target Sequences: | NM_005448 |
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