BMP10

bone morphogenetic protein 10

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

BMP10 (8)

Publications

No (8)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His-GST (2)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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Human BMP10 Protein (Recombinant) - LS-G104

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

24.4 kDa

Price:

2 µg/$268; 10 µg/$349

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Human BMP10 Protein (Recombinant GST, N-terminus) (aa317-424) - LS-G62270

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human BMP10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89980

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.08 kDa

Price:

20 µg/$215

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BMP10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113906

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.08 kDa

Price:

100 µg/$710

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Human BMP10 Protein (Recombinant GST) (Full Length) - LS-G33327

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.27 kDa

Price:

2 µg/$439

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Human BMP10 Protein (Recombinant 6His, N-terminus) (Ser22-Arg424) - LS-G26361

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

46 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human BMP10 Protein (Recombinant His-GST) (aa315-424) - LS-G14748

Source:

E. coli

Tag:

His-GST

Molecular Weight:

39.2 kDa

Price:

10 µg/$287; 50 µg/$477; 100 µg/$762; 200 µg/$952; 1 mg/$2,083; 500 µg/$1,613; 5 mg/$3,333; 2 mg/$2,272

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Mouse BMP10 Protein (Recombinant His-GST) (aa314-421) - LS-G14749

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.0 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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