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BMP1

bone morphogenetic protein 1

BMP1 encodes a Metallopeptidase M12A type protease that is comprised of an amino terminal signal peptide, prodomain and an astacin-like protease domain followed by CUB and EGF-like motifs. BMP1 protein has been shown to cleave chordin, the C-terminal propeptides of procollagen I, II, III and VII, pro-lysyl oxidase, probiglycan, and laminin-5, and its expression has been shown to induce cartilage and bone formation in vivo. At least six spliced variants have been reported. These share the N-terminal protease domain but differ in the C-terminus, and thus contain varying numbers of CUB and EGF-like domains.

Gene Name: bone morphogenetic protein 1
Family/Subfamily: Protease , Metallopeptidase M12A
Synonyms: BMP1, Bone morphogenetic protein 1, OI13, PCP-2, Procollagen C-proteinase-2, Procollagen C-proteinase, MTld, PCOLC, PCP-1, Procollagen C-endopeptidase, TLD, BMP-1, Mammalian tolloid, Mammalian tolloid protein, PCP
Target Sequences: NM_006129 NP_006120.1 P13497

Publications (1)

1
Cytokine expression in muscle following traumatic injury. Wesley M Jackson, Amber B Aragon, Jun Onodera, Steven M Koehler, Youngmi Ji, Jamie D Bulken-Hoover, Jared A Vogler, Rocky S Tuan, Leon J Nesti. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2011 October;29:1613-20. [Full Text Article] [PubMed:21452302] [PMC:PMC3150639]

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Products
Antibodies (37)
Primary (37)
BMP1 (37)
Human (29)
Mouse (17)
Rat (7)
Bovine (3)
Chimpanzee (3)
Dog (3)
Frog (1)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (6)
IHC-P (4)
WB (26)
ELISA (12)
IF (3)
Peptide-ELISA (2)
rabbit (34)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
Ig (1)
IgG (11)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (35)
OTI3E9 (2)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (1)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (15)
aa610-843 (8)
aa856-982 (8)
C-Terminus (7)
aa420-469 (4)
aa225-617 (1)
No (37)
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Frog, Mouse, Human
ELISA, WB
Unconjugated
100 µg/$832
BMP1 Antibody - Anti-BMP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BMP1.
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BMP1 Mouse anti-Human Monoclonal (OTI3E9) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
BMP1 Antibody - Anti-BMP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BMP1.
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BMP1 Mouse anti-Human Monoclonal (aa225-617) (Carrier-free) (OTI3E9) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
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BMP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
250 µl/$407
BMP1 Antibody - BMP1 / BMP-1 antibody Western Blot of ACHN. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Human Polyclonal (aa420-469) Antibody
Human
WB
Unconjugated
100 µl/$424
BMP1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BMP1 Goat anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
BMP1 Antibody - All lanes: Anti-BMP1 Antibody at 1:2000 dilution Lane 1: A549 whole cell lysate Lane 2: U-251 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 111 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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BMP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
BMP1 Antibody - Western blot of recombinant protein encoding a partial fragment of BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Mouse Polyclonal (aa856-982) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
BMP1 Antibody - Western blot of recombinant protein encoding a partial fragment of BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Mouse Polyclonal (aa856-982) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
BMP1 Antibody - Western blot of recombinant protein encoding a partial fragment of BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Mouse Polyclonal (aa856-982) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
BMP1 Antibody - Western blot of recombinant protein encoding a partial fragment of BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Mouse Polyclonal (aa856-982) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
BMP1 Antibody - Western blot of recombinant protein encoding a partial fragment of BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Mouse Polyclonal (aa856-982) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
BMP1 Antibody - Western blot of recombinant protein encoding a partial fragment of BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Mouse Polyclonal (aa856-982) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
BMP1 Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using BMP1 Polyclonal Antibody at dilution of 1:105(×200)
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BMP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC-P
Unconjugated
200 µl/$734
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
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BMP1 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
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BMP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P
Unconjugated
100 µg/$357
BMP1 Antibody - Western blot analysis of BMP1 using Jurkat whole cells lysates
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BMP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BMP1 Antibody - Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200.
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BMP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BMP1 Antibody - Immunofluorescence analysis of HeLa cells using BMP1 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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BMP1 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BMP1 Antibody - Western blot of recombinant BMP1 / BMP-1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP1 Rabbit anti-Human Polyclonal (aa610-843) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).