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BMI1 / PCGF4

BMI1 polycomb ring finger oncogene

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Gene Name: BMI1 polycomb ring finger oncogene
Synonyms: BMI1, BMI-1, Flvi-2/bmi-1, FLVI2/BMI1, PCGF4, Polycomb group protein Bmi1, Polycomb complex protein BMI-1, Dna-binding protein bmi-1, Polycomb group ring finger 4, RING finger protein 51, RNF51
Target Sequences: NM_005180 NP_005171.4 P35226

Publications (1)

1
Expression and survival significance of B-cell-specific Moloney murine leukemia virus integration site 1 and matrix metalloproteinase-9 in non-small-cell lung cancer. Mu M, Song Y, Zhang B. Oncology letters. 2016 12:3715-3722. (WB; Human) [Full Text Article] [PubMed:27900059] [PMC:PMC5104154] Related Antibodies: LS-C98479.

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ELISA Kits (3)
Sandwich (3)
BMI1 / PCGF4 (3)
Human (2)
Mouse (1)
96-Well Strip Plate (3)
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Cell Lysates (1)
Plasma (2)
Serum (2)
Tissue Homogenates (3)
BMI1 / PCGF4 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
BMI1 / PCGF4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
25 - 1600 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
BMI1 / PCGF4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).