BMF

Bcl2 modifying factor

Apoptosis is related to many diseases and development. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3-only proteins, including Bad, Bid, Bik, Hrk, Bim, Noxa, and PUMA, form a growing subclass of the Bcl-2 family. A novel BH3-only protein was recently identified in human and mouse and designated Bmf (for Bcl-2-modifying factor). The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiating the downstream apoptotic program. Bmf is constitutively expressed in many tissues.

☰ Filters

Products

Antibodies (52)

ELISA Kits (13)

Proteins (9)

Type

Over-Expression Lysate (2)

Primary (52)

Recombinant (7)

Sandwich (12)

Sandwich CLIA (1)

Target

BMF (74)

Reactivity

Human (54)

Mouse (9)

Rat (4)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Application

IHC (22)

IHC-P (10)

WB (46)

Flo (4)

ELISA (14)

ICC (5)

IF (4)

IP (4)

Peptide-ELISA (1)

Host

rabbit (34)

mouse (14)

rat (4)

Product Group

IHCPlus (1)

Isotype

IgG (19)

IgG1 (9)

IgG2a (5)

IgG2a,k (2)

IgG2b (2)

Clonality

monoclonal mc (18)

polyclonal pc (34)

Clone

12E10 (1)

17A9 (1)

9G10 (2)

OTI3E5 (2)

OTI3H5 (2)

OTI4F4 (2)

OTI5H2 (2)

OTI6F3 (2)

OTI7B3 (2)

OTI9B7 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (12)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

Carrier-free (7)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Preservative Free (2)

Unconjugated (37)

more less

Epitope

aa1-181 (8)

aa115-150 (7)

N-Terminus (4)

aa1-184 (2)

aa13-27 (1)

Publications

No (73)

Yes (1)

Sample Type

Cell Supernatant (1)

Plasma (8)

Serum (8)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (2)

Myc-DDK (Flag) (3)

Species

Human (8)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (1)

Select

BMF Antibody (clone 12E10) LS-C4125

Antibody:

BMF Rat anti-Mouse Monoclonal (12E10) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IP, WB

Format:

Unconjugated

Price:

100 µg/$801

Select

BMF Antibody (clone 9G10) LS-C4126

(4.1) Rating

(2) Publication(s)

Antibody:

BMF Rat anti-Mouse Monoclonal (9G10) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IP, WB

Format:

Unconjugated

Price:

100 µg/$771

Select

IHC-plus™ BMF Antibody LS-B458

(4.0) Rating

Antibody:

BMF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

BMF Antibody (aa13-27, clone 17A9) LS-C344948

Antibody:

BMF Rat anti-Mouse Monoclonal (aa13-27) (17A9) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, Flo, ICC, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$435

Select

BMF Antibody LS-C348966

Antibody:

BMF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

BMF Antibody (N-Terminus, Biotin) LS-C445373

Antibody:

BMF Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BMF Antibody (clone OTI6F3) LS-C340278

Antibody:

BMF Mouse anti-Human Monoclonal (OTI6F3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BMF Antibody (clone OTI6F3, Carrier-free) LS-C791254

Antibody:

BMF Mouse anti-Human Monoclonal (Carrier-free) (OTI6F3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BMF Antibody (clone OTI9B7) LS-C340280

Antibody:

BMF Mouse anti-Human Monoclonal (OTI9B7) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BMF Antibody (clone OTI9B7, Carrier-free) LS-C791255

Antibody:

BMF Mouse anti-Human Monoclonal (Carrier-free) (OTI9B7) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

Human BMF Protein (Recombinant His, N-Terminal) (aa1-181) - LS-G14886

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

24.0 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

Select

BMF Antibody LS-C419

Antibody:

BMF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

BMF Antibody (clone OTI3H5) LS-C340365

Antibody:

BMF Mouse anti-Human Monoclonal (OTI3H5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BMF Antibody (clone OTI3H5, Carrier-free) LS-C791352

Antibody:

BMF Mouse anti-Human Monoclonal (Carrier-free) (OTI3H5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BMF Antibody (clone OTI3E5) LS-C340279

Antibody:

BMF Mouse anti-Human Monoclonal (OTI3E5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

BMF Antibody (clone OTI3E5, Carrier-free) LS-C791252

Antibody:

BMF Mouse anti-Human Monoclonal (Carrier-free) (OTI3E5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BMF Antibody (Preservative Free) LS-C814732

Antibody:

BMF Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

BMF Antibody (aa115-150) LS-C326918

Antibody:

BMF Rabbit anti-Human Polyclonal (aa115-150) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

BMF Antibody (aa115-150, Biotin) LS-C275446

Antibody:

BMF Rabbit anti-Human Polyclonal (aa115-150) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

BMF Antibody (aa115-150, APC) LS-C275444

Antibody:

BMF Rabbit anti-Human Polyclonal (aa115-150) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• APC

• Unconjugated
• Biotin
• APC

Select

BMF Antibody (clone 9G10) LS-C344947

Antibody:

BMF Rat anti-Mouse Monoclonal (9G10) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IP, WB

Format:

Unconjugated

Price:

100 µg/$435

Select

BMF Antibody LS-C815972

Antibody:

BMF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

BMF Antibody (aa1-184) LS-C378902

Antibody:

BMF Rabbit anti-Human Polyclonal (aa1-184) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

BMF Antibody (aa1-184) LS-C378901

Antibody:

BMF Rabbit anti-Human Polyclonal (aa1-184) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

BMF Antibody (aa115-150) LS-C98849

Antibody:

BMF Rabbit anti-Human Polyclonal (aa115-150) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Viewing 1-25 of 74 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.