BMF

Bcl2 modifying factor

Apoptosis is related to many diseases and development. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3-only proteins, including Bad, Bid, Bik, Hrk, Bim, Noxa, and PUMA, form a growing subclass of the Bcl-2 family. A novel BH3-only protein was recently identified in human and mouse and designated Bmf (for Bcl-2-modifying factor). The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiating the downstream apoptotic program. Bmf is constitutively expressed in many tissues.

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Products

ELISA Kits (13)

Type

Sandwich (12)

Sandwich CLIA (1)

Target

BMF (13)

Reactivity

Human (3)

Mouse (3)

Rat (2)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (12)

Publications

No (13)

Sample Type

Cell Supernatant (1)

Plasma (8)

Serum (8)

Tissue Homogenates (1)

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Human BMF (Sandwich ELISA) ELISA Kit - LS-F49792

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse BMF (Sandwich ELISA) ELISA Kit - LS-F49796

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Chicken BMF (Sandwich ELISA) ELISA Kit - LS-F41629

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit BMF (Sandwich ELISA) ELISA Kit - LS-F41630

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey BMF (Sandwich ELISA) ELISA Kit - LS-F41631

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine BMF (Sandwich ELISA) ELISA Kit - LS-F41632

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Sheep BMF (Sandwich ELISA) ELISA Kit - LS-F41633

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

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Mouse BMF (CLIA) ELISA Kit - LS-F75097

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$669

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Rat BMF (Sandwich ELISA) ELISA Kit - LS-F67070

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human BMF (Sandwich ELISA) ELISA Kit - LS-F24204

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human BMF (Sandwich ELISA) ELISA Kit - LS-F33755

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

93.75 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat BMF (Sandwich ELISA) ELISA Kit - LS-F38590

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse BMF (Sandwich ELISA) ELISA Kit - LS-F38259

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Viewing 1-13 of 13 product results

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