Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation.
|Gene Name:||biogenesis of lysosomal organelles complex-1, subunit 2|
|Synonyms:||BLOC1S2, Centrosome protein oncogene, Centrosome-associated protein, CEAP, RP11-316M21.4, BLOC-1 subunit 2, BLOS2, Centrosomal 10 kDa protein|
|Target Sequences:||Q6QNY1 Q6QNY1|
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