BLOC1S1

biogenesis of lysosomal organelles complex-1, subunit 1

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 and NDUFA9.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

BLOC1S1 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human BLOC1S1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66902

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.1 kDa

Price:

20 µg/$1,107

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Human BLOC1S1 Protein (Recombinant GST, N-terminus) (aa31-124) - LS-G58668

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human BLOC1S1 Protein (Recombinant GST) (Full Length) - LS-G28597

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

40.7 kDa

Price:

2 µg/$439

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Human BLOC1S1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78686

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.1 kDa

Price:

20 µg/$150

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BLOC1S1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118549

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.1 kDa

Price:

100 µg/$494

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