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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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We could not find product '(ID:368582)'. Here are some alternate products to this target that might be of interest to you.



BLK

B lymphoid tyrosine kinase

Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Specifically binds and phosphorylates CD79A at 'Tyr-188'and 'Tyr-199', as well as CD79B at 'Tyr-196' and 'Tyr-207'. Phosphorylates also the immunoglobulin G receptors FCGR2A, FCGR2B and FCGR2C. With FYN and LYN, plays an essential role in pre-B-cell receptor (pre-BCR)-mediated NF-kappa-B activation. Contributes also to BTK activation by indirectly stimulating BTK intramolecular autophosphorylation. In pancreatic islets, acts as a modulator of beta-cells function through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.

Gene Name: B lymphoid tyrosine kinase
Family/Subfamily: Protein Kinase , Src
Synonyms: BLK, Blk kinase, B lymphocyte kinase, B lymphoid tyrosine kinase, MODY11, Protein kinase blk, Protein tyrosine kinase blk, B lymphoid kinase, p55-Blk, Tyrosine-protein kinase Blk
Target Sequences: NM_001715 NP_001706.2 P51451

Viewing 1-25 of 62 items
BLK Antibody - Anti-BLK antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Goat Polyclonal to Human BLK
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
BLK Antibody - BLK Antibody in Immunofluorescence (IF)
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Mouse Monoclonal [clone 1000000] (IgG1) to Human BLK
Human
Flo, ICC, IF, WB
Unconjugated
100µl   $405.00
BLK Antibody - Immunofluorescence (IF) analysis of HeLa cells using Blk Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Select
Mouse Monoclonal (IgG1) to Human BLK
Human
ELISA, Flo, IF, WB
Unconjugated
100µl   $345.00
Select
Mouse Monoclonal (IgG1) to Human BLK
Human
ELISA, Flo, ICC, WB
Unconjugated
50µl   1mg/ml   $315.00; 100µl   1mg/ml   $375.00; 200µl   1mg/ml   $435.00
BLK Antibody - Immunofluorescence of HeLa cells using BLK mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Select
Mouse Monoclonal [clone 1E6] (IgG1) to Human BLK
Human
ELISA, Flo, IF, WB
Unconjugated
100µl   $345.00
BLK Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $285.00; 100µl   $385.00
BLK Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
Rabbit Polyclonal to Human BLK
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
BLK Antibody
Select
Mouse Monoclonal [clone 9D10D1] (IgG2a) to Human BLK
Human
ELISA, IHC, WB
Unconjugated
100µl   $365.00
BLK Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast tissue (A), lymph tissue (B) and skin carcinoma (C), showing membrane localization with DAB staining using Blk Monoclonal Antibody.
Select
Mouse Monoclonal (IgG1) to Human BLK
Human
ELISA, IHC, WB
Unconjugated
100µl   $345.00
BLK Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung carcinoma (A), lymph tissue (B) and skin carcinoma (C), showing membrane localization with DAB staining using Blk Monoclonal Antibody.
Select
Mouse Monoclonal (IgG1) to Human BLK
Human
ELISA, IHC, WB
Unconjugated
100µl   $345.00
BLK Antibody
Select
Mouse Monoclonal [clone 9D10B7] (IgG1) to Human BLK
Human
ELISA, IHC, WB
Unconjugated
100µl   $365.00
BLK Antibody
Select
Mouse Monoclonal [clone 9D10B7H6, 9D10A8F8] (IgG1) to Human BLK
Human
ELISA, IHC, WB
Unconjugated
100µl   $315.00
BLK Antibody - Western blot of Blk antibody
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
BLK Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human BLK
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $285.00; 100µl   $385.00
BLK Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast tissue (A), lymph tissue (B) and skin carcinoma (C), showing membrane localization with DAB staining using Blk Monoclonal Antibody.
Select
Mouse Monoclonal (IgG2a) to Human BLK
Human
ELISA, IHC
Unconjugated
100µl   $345.00
BLK Antibody - BLK monoclonal antibody (M01), clone 3E5-3A8. Western Blot analysis of BLK expression in A-431.
Select
Mouse Monoclonal [clone 3E5-3A8] (IgG1,k) to Human BLK
Human
ELISA, WB
Unconjugated
100µg   $365.00
BLK Antibody - Immunohistochemical analysis of BLK staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human BLK
Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $275.00
Select
Rabbit Polyclonal (IgG) to Human BLK
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00

Viewing 1-25 of 62 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).