BLIMP1 / PRDM1

Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production. Gong D, Malek TR. Journal of immunology (Baltimore, Md. : 1950). 2007 178:242-52. [PubMed:17182561]

Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1. John SA, Clements JL, Russell LM, Garrett-Sinha LA. The Journal of biological chemistry. 2008 283:951-62. [PubMed:17977828]

Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice. Robertson EJ, Charatsi I, Joyner CJ, Koonce CH, Morgan M, Islam A, Paterson C, Lejsek E, Arnold SJ, Kallies A, Nutt SL, Bikoff EK. Development (Cambridge, England). 2007 134:4335-45. [PubMed:18039967]

Recurrent inactivation of the PRDM1 gene in primary central nervous system lymphoma. Courts C, Montesinos-Rongen M, Brunn A, Bug S, Siemer D, Hans V, Blmcke I, Klapper W, Schaller C, Wiestler OD, Kppers R, Siebert R, Deckert M. Journal of neuropathology and experimental neurology. 2008 67:720-7. [PubMed:18596541]

RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1. Wang X, Belguise K, O'Neill CF, Snchez-Morgan N, Romagnoli M, Eddy SF, Mineva ND, Yu Z, Min C, Trinkaus-Randall V, Chalbos D, Sonenshein GE. Molecular and cellular biology. 2009 29:3832-44. [PubMed:19433448] [PMC:PMC2704748]

Peroxisome proliferator-activated receptor gamma ligands enhance human B cell antibody production and differentiation. Garcia-Bates TM, Baglole CJ, Bernard MP, Murant TI, Simpson-Haidaris PJ, Phipps RP. Journal of immunology (Baltimore, Md. : 1950). 2009 183:6903-12. [PubMed:19915048] [PMC:PMC2821683]

Blimp1-mediated repression of negative regulators is required for osteoclast differentiation. Nishikawa K, Nakashima T, Hayashi M, Fukunaga T, Kato S, Kodama T, Takahashi S, Calame K, Takayanagi H. Proceedings of the National Academy of Sciences of the United States of America. 2010 107:3117-22. [PubMed:20133620] [PMC:PMC2840297]

Identifying regulatory B cells (B10 cells) that produce IL-10 in mice. Matsushita T, Tedder TF. Methods in molecular biology (Clifton, N.J.). 2011 677:99-111. [PubMed:20941605]

NANOS3 function in human germ cell development. Julaton VT, Reijo Pera RA. Human molecular genetics. 2011 20:2238-50. [PubMed:21421998] [PMC:PMC3090199]

SUMOylation of Blimp-1 promotes its proteasomal degradation. Shimshon L, Michaeli A, Hadar R, Nutt SL, David Y, Navon A, Waisman A, Tirosh B. FEBS letters. 2011 585:2405-9. [PubMed:21722636]

Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. Maseda D, Smith SH, DiLillo DJ, Bryant JM, Candando KM, Weaver CT, Tedder TF. Journal of immunology (Baltimore, Md. : 1950). 2012 188:1036-48. [PubMed:22198952] [PMC:PMC3262922]

Bim regulates B-cell receptor-mediated apoptosis in the presence of CD40 signaling in CD40-pre-activated splenic B cells differentiating into plasma cells. Gao Y, Kazama H, Yonehara S. International immunology. 2012 24:283-92. [PubMed:22301689]

Soluble factors produced by activated CD4+ T cells modulate EBV latency. Nagy N, Adori M, Rasul A, Heuts F, Salamon D, Ujvri D, Madapura HS, Leveau B, Klein G, Klein E. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:1512-7. (WB; Human) [PubMed:22307606] [PMC:PMC3277165]

IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation. Altin JA, Goodnow CC, Cook MC. Journal of immunology (Baltimore, Md. : 1950). 2012 188:5478-88. (Flo; Mouse) [PubMed:22547705]

IL-2 requirement for human plasma cell generation: coupling differentiation and proliferation by enhancing MAPK-ERK signaling. Le Gallou S, Caron G, Delaloy C, Rossille D, Tarte K, Fest T. Journal of immunology (Baltimore, Md. : 1950). 2012 189:161-73. (WB; Human) [PubMed:22634617]

Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells. Ramon S, Gao F, Serhan CN, Phipps RP. Journal of immunology (Baltimore, Md. : 1950). 2012 189:1036-42. (WB; Human) [PubMed:22711890] [PMC:PMC3392531]

Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactions. Morgan MA, Mould AW, Li L, Robertson EJ, Bikoff EK. Molecular and cellular biology. 2012 32:3403-13. (IP; Human) [PubMed:22733990] [PMC:PMC3422002]

Duodenal follicular lymphoma lacks AID but expresses BACH2 and has memory B-cell characteristics. Takata K, Sato Y, Nakamura N, Tokunaka M, Miki Y, Yukie Kikuti Y, Igarashi K, Ito E, Harigae H, Kato S, Hayashi E, Oka T, Hoshii Y, Tari A, Okada H, Mohamad AA, Maeda Y, Tanimoto M, Kinoshita T, Yoshino T. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013 26:22-31. (IHC; Human) [PubMed:22899287]

Receptor cross-talk spatially restricts p-ERK during TLR4 stimulation of autoreactive B cells. Lee SR, Rutan JA, Monteith AJ, Jones SZ, Kang SA, Krum KN, Kilmon MA, Roques JR, Wagner NJ, Clarke SH, Vilen BJ. Journal of immunology (Baltimore, Md. : 1950). 2012 189:3859-68. (WB; Mouse) [PubMed:22984080] [PMC:PMC3466401]

B lymphocyte-induced maturation protein 1 (BLIMP-1) attenuates autoimmune diabetes in NOD mice by suppressing Th1 and Th17 cells. Lin MH, Chou FC, Yeh LT, Fu SH, Chiou HY, Lin KI, Chang DM, Sytwu HK. Diabetologia. 2013 56:136-46. (WB; Mouse) [PubMed:23052053]